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High Throughput Screening to Identify Selective and Nonpeptidomimetic Proteasome Inhibitors As Antimalarials.
Mata-Cantero L, Xie SC, García M, Coyle J, Fernandez R, Cabrera AC, Gillett DL, Crespo B, Gamo FJ, Fernández E, Tilley L, Gomez-Lorenzo MG. Mata-Cantero L, et al. Among authors: fernandez e, fernandez r. ACS Infect Dis. 2021 Jun 11;7(6):1818-1832. doi: 10.1021/acsinfecdis.1c00110. Epub 2021 May 28. ACS Infect Dis. 2021. PMID: 34044540 Free article.
Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis.
Guardia A, Baiget J, Cacho M, Pérez A, Ortega-Guerra M, Nxumalo W, Khanye SD, Rullas J, Ortega F, Jiménez E, Pérez-Herrán E, Fraile-Gabaldón MT, Esquivias J, Fernández R, Porras-De Francisco E, Encinas L, Alonso M, Giordano I, Rivero C, Miguel-Siles J, Osende JG, Badiola KA, Rutledge PJ, Todd MH, Remuiñán M, Alemparte C. Guardia A, et al. Among authors: fernandez r. J Med Chem. 2018 Dec 27;61(24):11327-11340. doi: 10.1021/acs.jmedchem.8b01533. Epub 2018 Dec 12. J Med Chem. 2018. PMID: 30457865
A new 'golden age' for the antitubercular target InhA.
Rožman K, Sosič I, Fernandez R, Young RJ, Mendoza A, Gobec S, Encinas L. Rožman K, et al. Among authors: fernandez r. Drug Discov Today. 2017 Mar;22(3):492-502. doi: 10.1016/j.drudis.2016.09.009. Epub 2016 Sep 20. Drug Discov Today. 2017. PMID: 27663094 Review.
N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity.
Guardia A, Gulten G, Fernandez R, Gómez J, Wang F, Convery M, Blanco D, Martínez M, Pérez-Herrán E, Alonso M, Ortega F, Rullás J, Calvo D, Mata L, Young R, Sacchettini JC, Mendoza-Losana A, Remuiñán M, Ballell Pages L, Castro-Pichel J. Guardia A, et al. Among authors: fernandez r. ChemMedChem. 2016 Apr 5;11(7):687-701. doi: 10.1002/cmdc.201600020. Epub 2016 Mar 2. ChemMedChem. 2016. PMID: 26934341
Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist.
Eastwood P, Esteve C, González J, Fonquerna S, Aiguadé J, Carranco I, Doménech T, Aparici M, Miralpeix M, Albertí J, Córdoba M, Fernández R, Pont M, Godessart N, Prats N, Loza MI, Cadavid MI, Nueda A, Vidal B. Eastwood P, et al. Among authors: fernandez r. ACS Med Chem Lett. 2010 Dec 20;2(3):213-8. doi: 10.1021/ml100249e. eCollection 2011 Mar 10. ACS Med Chem Lett. 2010. PMID: 24900298 Free PMC article.
Association of antenatal or neonatal SARS-COV-2 exposure with developmental and respiratory outcomes, and healthcare usage in early childhood: a national prospective cohort study.
Jackson R, Cornish R, Daskalopoulou Z, Gale C, Hurd M, Johnson S, Knight M, Kurinczuk JJ, Woodward K, Chakkarapani E; SINEPOST collaborative group. Jackson R, et al. EClinicalMedicine. 2024 May 3;72:102628. doi: 10.1016/j.eclinm.2024.102628. eCollection 2024 Jun. EClinicalMedicine. 2024. PMID: 38737004 Free PMC article.
2,651 results