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Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.
Sušac L, Vuong MT, Thomas C, von Bülow S, O'Brien-Ball C, Santos AM, Fernandes RA, Hummer G, Tampé R, Davis SJ. Sušac L, et al. Among authors: fernandes ra. Cell. 2022 Aug 18;185(17):3201-3213.e19. doi: 10.1016/j.cell.2022.07.010. Cell. 2022. PMID: 35985289 Free PMC article.
What controls T cell receptor phosphorylation?
Fernandes RA, Yu C, Carmo AM, Evans EJ, van der Merwe PA, Davis SJ. Fernandes RA, et al. Cell. 2010 Sep 3;142(5):668-9. doi: 10.1016/j.cell.2010.08.018. Cell. 2010. PMID: 20813251 Free article. No abstract available.
The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins.
James JR, McColl J, Oliveira MI, Dunne PD, Huang E, Jansson A, Nilsson P, Sleep DL, Gonçalves CM, Morgan SH, Felce JH, Mahen R, Fernandes RA, Carmo AM, Klenerman D, Davis SJ. James JR, et al. Among authors: fernandes ra. J Biol Chem. 2011 Sep 16;286(37):31993-2001. doi: 10.1074/jbc.M111.219212. Epub 2011 Jul 13. J Biol Chem. 2011. PMID: 21757710 Free PMC article.
On the Control of TCR Phosphorylation.
Fernandes RA, Huo J, Lui Y, Felce JH, Davis SJ. Fernandes RA, et al. Front Immunol. 2012 May 7;3:92. doi: 10.3389/fimmu.2012.00092. eCollection 2012. Front Immunol. 2012. PMID: 22566970 Free PMC article. No abstract available.
Initiation of T cell signaling by CD45 segregation at 'close contacts'.
Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jönsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJC, Klenerman D, Aricescu AR, Davis SJ. Chang VT, et al. Among authors: fernandes ra. Nat Immunol. 2016 May;17(5):574-582. doi: 10.1038/ni.3392. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998761 Free PMC article.
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Jönsson P, Southcombe JH, Santos AM, Huo J, Fernandes RA, McColl J, Lever M, Evans EJ, Hudson A, Chang VT, Hanke T, Godkin A, Dunne PD, Horrocks MH, Palayret M, Screaton GR, Petersen J, Rossjohn J, Fugger L, Dushek O, Xu XN, Davis SJ, Klenerman D. Jönsson P, et al. Among authors: fernandes ra. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5682-7. doi: 10.1073/pnas.1513918113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114505 Free PMC article.
Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.
Fritzsche M, Fernandes RA, Chang VT, Colin-York H, Clausen MP, Felce JH, Galiani S, Erlenkämper C, Santos AM, Heddleston JM, Pedroza-Pacheco I, Waithe D, de la Serna JB, Lagerholm BC, Liu TL, Chew TL, Betzig E, Davis SJ, Eggeling C. Fritzsche M, et al. Among authors: fernandes ra. Sci Adv. 2017 Jun 21;3(6):e1603032. doi: 10.1126/sciadv.1603032. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28691087 Free PMC article.
Capturing resting T cells: the perils of PLL.
Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF. Santos AM, et al. Among authors: fernandes ra. Nat Immunol. 2018 Mar;19(3):203-205. doi: 10.1038/s41590-018-0048-8. Epub 2018 Feb 23. Nat Immunol. 2018. PMID: 29476188 Free PMC article. No abstract available.
395 results