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Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics.
Costa C, Pereira S, Lima L, Peixoto A, Fernandes E, Neves D, Neves M, Gaiteiro C, Tavares A, Gil da Costa RM, Cruz R, Amaro T, Oliveira PA, Ferreira JA, Santos LL. Costa C, et al. Among authors: fernandes e. PLoS One. 2015 Nov 16;10(11):e0141253. doi: 10.1371/journal.pone.0141253. eCollection 2015. PLoS One. 2015. PMID: 26569621 Free PMC article.
Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension.
Peixoto A, Fernandes E, Gaiteiro C, Lima L, Azevedo R, Soares J, Cotton S, Parreira B, Neves M, Amaro T, Tavares A, Teixeira F, Palmeira C, Rangel M, Silva AM, Reis CA, Santos LL, Oliveira MJ, Ferreira JA. Peixoto A, et al. Among authors: fernandes e. Oncotarget. 2016 Sep 27;7(39):63138-63157. doi: 10.18632/oncotarget.11257. Oncotarget. 2016. PMID: 27542232 Free PMC article.
Targeted O-glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced-stage bladder tumours.
Cotton S, Azevedo R, Gaiteiro C, Ferreira D, Lima L, Peixoto A, Fernandes E, Neves M, Neves D, Amaro T, Cruz R, Tavares A, Rangel M, Silva AMN, Santos LL, Ferreira JA. Cotton S, et al. Among authors: fernandes e. Mol Oncol. 2017 Aug;11(8):895-912. doi: 10.1002/1878-0261.12035. Epub 2017 Mar 2. Mol Oncol. 2017. PMID: 28156048 Free PMC article.
Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer.
Peixoto A, Ferreira D, Azevedo R, Freitas R, Fernandes E, Relvas-Santos M, Gaiteiro C, Soares J, Cotton S, Teixeira B, Paulo P, Lima L, Palmeira C, Martins G, Oliveira MJ, Silva AMN, Santos LL, Ferreira JA. Peixoto A, et al. Among authors: fernandes e. J Exp Clin Cancer Res. 2021 Jun 9;40(1):191. doi: 10.1186/s13046-021-01988-6. J Exp Clin Cancer Res. 2021. PMID: 34108014 Free PMC article.
Response of high-risk of recurrence/progression bladder tumours expressing sialyl-Tn and sialyl-6-T to BCG immunotherapy.
Lima L, Severino PF, Silva M, Miranda A, Tavares A, Pereira S, Fernandes E, Cruz R, Amaro T, Reis CA, Dall'Olio F, Amado F, Videira PA, Santos L, Ferreira JA. Lima L, et al. Among authors: fernandes e. Br J Cancer. 2013 Oct 15;109(8):2106-14. doi: 10.1038/bjc.2013.571. Epub 2013 Sep 24. Br J Cancer. 2013. PMID: 24064971 Free PMC article.
P53 and cancer-associated sialylated glycans are surrogate markers of cancerization of the bladder associated with Schistosoma haematobium infection.
Santos J, Fernandes E, Ferreira JA, Lima L, Tavares A, Peixoto A, Parreira B, Correia da Costa JM, Brindley PJ, Lopes C, Santos LL. Santos J, et al. Among authors: fernandes e. PLoS Negl Trop Dis. 2014 Dec 11;8(12):e3329. doi: 10.1371/journal.pntd.0003329. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25502795 Free PMC article.
1,116 results