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Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein.
Velázquez-López I, Valdés-García G, Romero Romero S, Maya Martínez R, Leal-Cervantes AI, Costas M, Sánchez-López R, Amero C, Pastor N, Fernández Velasco DA. Velázquez-López I, et al. Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1656-1666. doi: 10.1016/j.bbagen.2018.04.014. Epub 2018 Apr 15. Biochim Biophys Acta Gen Subj. 2018. PMID: 29669263
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
Romero-Romero S, Costas M, Silva Manzano DA, Kordes S, Rojas-Ortega E, Tapia C, Guerra Y, Shanmugaratnam S, Rodríguez-Romero A, Baker D, Höcker B, Fernández-Velasco DA. Romero-Romero S, et al. Among authors: fernandez velasco da. J Mol Biol. 2021 Sep 3;433(18):167153. doi: 10.1016/j.jmb.2021.167153. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271011 Free PMC article.
Structural, thermodynamic and catalytic characterization of an ancestral triosephosphate isomerase reveal early evolutionary coupling between monomer association and function.
Schulte-Sasse M, Pardo-Ávila F, Pulido-Mayoral NO, Vázquez-Lobo A, Costas M, García-Hernández E, Rodríguez-Romero A, Fernández-Velasco DA. Schulte-Sasse M, et al. FEBS J. 2019 Mar;286(5):882-900. doi: 10.1111/febs.14741. Epub 2019 Jan 15. FEBS J. 2019. PMID: 30589511 Free article.
Stabilizing an amyloidogenic λ6 light chain variable domain.
Luna-Martínez OD, Hernández-Santoyo A, Villalba-Velázquez MI, Sánchez-Alcalá R, Fernández-Velasco DA, Becerril B. Luna-Martínez OD, et al. FEBS J. 2017 Nov;284(21):3702-3717. doi: 10.1111/febs.14265. Epub 2017 Oct 12. FEBS J. 2017. PMID: 28898537 Free article.
Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Castro-Torres E, Jiménez-Sandoval P, Romero-Romero S, Fuentes-Pascacio A, López-Castillo LM, Díaz-Quezada C, Fernández-Velasco DA, Torres-Larios A, Brieba LG. Castro-Torres E, et al. Among authors: fernandez velasco da. Plant J. 2019 Sep;99(5):950-964. doi: 10.1111/tpj.14375. Epub 2019 Jun 13. Plant J. 2019. PMID: 31034710 Free article.
42 results