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Orexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity.
Mol Metab. 2023 Jun;72:101713. doi: 10.1016/j.molmet.2023.101713. Epub 2023 Mar 26.
Mol Metab. 2023.
PMID: 36977433
Free PMC article.
Positive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer's disease.
Forte N, Fernández-Rilo AC, Palomba L, Marfella B, Piscitelli F, De Girolamo P, Di Costanzo A, Di Marzo V, Cristino L.
Forte N, et al. Among authors: fernandez rilo ac.
Front Aging Neurosci. 2022 Nov 16;14:1004002. doi: 10.3389/fnagi.2022.1004002. eCollection 2022.
Front Aging Neurosci. 2022.
PMID: 36466600
Free PMC article.
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Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice.
Forte N, Boccella S, Tunisi L, Fernández-Rilo AC, Imperatore R, Iannotti FA, De Risi M, Iannotta M, Piscitelli F, Capasso R, De Girolamo P, De Leonibus E, Maione S, Di Marzo V, Cristino L.
Forte N, et al. Among authors: fernandez rilo ac.
Nat Commun. 2021 Oct 21;12(1):6137. doi: 10.1038/s41467-021-26388-4.
Nat Commun. 2021.
PMID: 34675233
Free PMC article.
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Orexin-A/Hypocretin-1 Controls the VTA-NAc Mesolimbic Pathway via Endocannabinoid-Mediated Disinhibition of Dopaminergic Neurons in Obese Mice.
Tunisi L, D'Angelo L, Fernández-Rilo AC, Forte N, Piscitelli F, Imperatore R, de Girolamo P, Di Marzo V, Cristino L.
Tunisi L, et al. Among authors: fernandez rilo ac.
Front Synaptic Neurosci. 2021 Feb 4;13:622405. doi: 10.3389/fnsyn.2021.622405. eCollection 2021.
Front Synaptic Neurosci. 2021.
PMID: 33613258
Free PMC article.
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Obesity Affects the Microbiota-Gut-Brain Axis and the Regulation Thereof by Endocannabinoids and Related Mediators.
Forte N, Fernández-Rilo AC, Palomba L, Di Marzo V, Cristino L.
Forte N, et al. Among authors: fernandez rilo ac.
Int J Mol Sci. 2020 Feb 25;21(5):1554. doi: 10.3390/ijms21051554.
Int J Mol Sci. 2020.
PMID: 32106469
Free PMC article.
Review.
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Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier.
Tunisi L, Forte N, Fernández-Rilo AC, Mavaro I, Capasso R, D'Angelo L, Milić N, Cristino L, Di Marzo V, Palomba L.
Tunisi L, et al. Among authors: fernandez rilo ac.
Front Endocrinol (Lausanne). 2019 Apr 10;10:219. doi: 10.3389/fendo.2019.00219. eCollection 2019.
Front Endocrinol (Lausanne). 2019.
PMID: 31024456
Free PMC article.
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