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The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome.
Marín-Prida J, Rodríguez-Ulloa A, Besada V, Llopiz-Arzuaga A, Batista NV, Hernández-González I, Pavón-Fuentes N, Marciano Vieira ÉL, Falcón-Cama V, Acosta EF, Martínez-Donato G, Cervantes-Llanos M, Lingfeng D, González LJ, Fernández-Massó JR, Guillén-Nieto G, Pentón-Arias E, Amaral FA, Teixeira MM, Pentón-Rol G. Marín-Prida J, et al. Among authors: fernandez masso jr. Front Immunol. 2023 Oct 23;14:1227268. doi: 10.3389/fimmu.2023.1227268. eCollection 2023. Front Immunol. 2023. PMID: 37936684 Free PMC article.
Beneficial effects of oral administration of C-Phycocyanin and Phycocyanobilin in rodent models of experimental autoimmune encephalomyelitis.
Cervantes-Llanos M, Lagumersindez-Denis N, Marín-Prida J, Pavón-Fuentes N, Falcon-Cama V, Piniella-Matamoros B, Camacho-Rodríguez H, Fernández-Massó JR, Valenzuela-Silva C, Raíces-Cruz I, Pentón-Arias E, Teixeira MM, Pentón-Rol G. Cervantes-Llanos M, et al. Among authors: fernandez masso jr. Life Sci. 2018 Feb 1;194:130-138. doi: 10.1016/j.lfs.2017.12.032. Epub 2017 Dec 27. Life Sci. 2018. PMID: 29287781
Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis.
Marín-Prida J, Pavón-Fuentes N, Lagumersindez-Denis N, Camacho-Rodríguez H, García-Soca AM, Sarduy-Chávez RC, Vieira ÉLM, Carvalho-Tavares J, Falcón-Cama V, Fernández-Massó JR, Hernández-González I, Martínez-Donato G, Guillén-Nieto G, Pentón-Arias E, Teixeira MM, Pentón-Rol G. Marín-Prida J, et al. Among authors: fernandez masso jr. Front Immunol. 2022 Nov 3;13:1036200. doi: 10.3389/fimmu.2022.1036200. eCollection 2022. Front Immunol. 2022. PMID: 36405721 Free PMC article.
Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.
Marín-Prida J, Pavón-Fuentes N, Llópiz-Arzuaga A, Fernández-Massó JR, Delgado-Roche L, Mendoza-Marí Y, Santana SP, Cruz-Ramírez A, Valenzuela-Silva C, Nazábal-Gálvez M, Cintado-Benítez A, Pardo-Andreu GL, Polentarutti N, Riva F, Pentón-Arias E, Pentón-Rol G. Marín-Prida J, et al. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):49-60. doi: 10.1016/j.taap.2013.05.021. Epub 2013 Jun 2. Toxicol Appl Pharmacol. 2013. PMID: 23732081
Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice.
Pentón-Rol G, Lagumersindez-Denis N, Muzio L, Bergami A, Furlan R, Fernández-Massó JR, Nazabal-Galvez M, Llópiz-Arzuaga A, Herrera-Rolo T, Veliz-Rodriguez T, Polentarutti N, Marín-Prida J, Raíces-Cruz I, Valenzuela-Silva C, Teixeira MM, Pentón-Arias E. Pentón-Rol G, et al. Among authors: fernandez masso jr. J Neuroimmune Pharmacol. 2016 Mar;11(1):153-67. doi: 10.1007/s11481-015-9642-9. Epub 2015 Nov 10. J Neuroimmune Pharmacol. 2016. PMID: 26556034
Comparative proteomics analysis of the antitumor effect of CIGB-552 peptide in HT-29 colon adenocarcinoma cells.
Núñez de Villavicencio-Díaz T, Ramos Gómez Y, Oliva Argüelles B, Fernández Masso JR, Rodríguez-Ulloa A, Cruz García Y, Guirola-Cruz O, Perez-Riverol Y, Javier González L, Tiscornia I, Victoria S, Bollati-Fogolín M, Besada Pérez V, Guerra Vallespi M. Núñez de Villavicencio-Díaz T, et al. Among authors: fernandez masso jr. J Proteomics. 2015 Aug 3;126:163-71. doi: 10.1016/j.jprot.2015.05.024. Epub 2015 May 24. J Proteomics. 2015. PMID: 26013411
Data for comparative proteomics analysis of the antitumor effect of CIGB-552 peptide in HT-29 colon adenocarcinoma cells.
Núñez de Villavicencio-Díaz T, Ramos Gómez Y, Oliva Argüelles B, Fernández Masso JR, Rodríguez-Ulloa A, Cruz García Y, Guirola-Cruz O, Perez-Riverol Y, Javier González L, Tiscornia I, Victoria S, Bollati-Fogolín M, Besada Pérez V, Guerra Vallespi M. Núñez de Villavicencio-Díaz T, et al. Among authors: fernandez masso jr. Data Brief. 2015 Jul 8;4:468-73. doi: 10.1016/j.dib.2015.06.024. eCollection 2015 Sep. Data Brief. 2015. PMID: 26306321 Free PMC article.
Formulation matters! A spectroscopic and molecular dynamics investigation on the peptide CIGB552 as itself and in its therapeutical formulation.
Savioli M, Antonelli L, Bocchinfuso G, Cavalieri F, Cimino R, Gatto E, Placidi E, Fernandez Masso JR, Garay Perez H, Santana H, Guerra-Vallespi M, Venanzi M. Savioli M, et al. Among authors: fernandez masso jr. J Pept Sci. 2022 Jan;28(1):e3356. doi: 10.1002/psc.3356. Epub 2021 Jun 10. J Pept Sci. 2022. PMID: 34114297
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