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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS. Saha I, et al. Among authors: fernandez busnadiego r. Nat Commun. 2023 Feb 2;14(1):560. doi: 10.1038/s41467-023-36058-2. Nat Commun. 2023. PMID: 36732333 Free PMC article.
In Situ Architecture and Cellular Interactions of PolyQ Inclusions.
Bäuerlein FJB, Saha I, Mishra A, Kalemanov M, Martínez-Sánchez A, Klein R, Dudanova I, Hipp MS, Hartl FU, Baumeister W, Fernández-Busnadiego R. Bäuerlein FJB, et al. Cell. 2017 Sep 21;171(1):179-187.e10. doi: 10.1016/j.cell.2017.08.009. Epub 2017 Sep 7. Cell. 2017. PMID: 28890085 Free article.
The cryo-electron microscopy structure of huntingtin.
Guo Q, Bin Huang, Cheng J, Seefelder M, Engler T, Pfeifer G, Oeckl P, Otto M, Moser F, Maurer M, Pautsch A, Baumeister W, Fernández-Busnadiego R, Kochanek S. Guo Q, et al. Nature. 2018 Mar 1;555(7694):117-120. doi: 10.1038/nature25502. Epub 2018 Feb 21. Nature. 2018. PMID: 29466333 Free PMC article.
Molecular and structural architecture of polyQ aggregates in yeast.
Gruber A, Hornburg D, Antonin M, Krahmer N, Collado J, Schaffer M, Zubaite G, Lüchtenborg C, Sachsenheimer T, Brügger B, Mann M, Baumeister W, Hartl FU, Hipp MS, Fernández-Busnadiego R. Gruber A, et al. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3446-E3453. doi: 10.1073/pnas.1717978115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581260 Free PMC article.
37 results