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The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection.
Fernández JJ, Marín A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, Villalón-Letelier F, Yildiz S, Pérez E, Rathnasinghe R, Cupic A, Kehrer T, Uccellini MB, Alonso S, Martínez F, McGovern BL, Clark JJ, Sharma P, Bayón Y, Alonso A, Albrecht RA, White KM, Schotsaert M, Miorin L, Stewart JP, Hiscox JA, Gupta RK, Irigoyen N, García-Sastre A, Crespo MS, Fernández N. Fernández JJ, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 20;1870(5):167193. doi: 10.1016/j.bbadis.2024.167193. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38648902
Innate IRE1α-XBP1 activation by viral single-stranded RNA and its influence on lung cytokine production during SARS-CoV-2 pneumonia.
Fernández JJ, Mancebo C, Garcinuño S, March G, Alvarez Y, Alonso S, Inglada L, Blanco J, Orduña A, Montero O, Sandoval TA, Cubillos-Ruiz JR, Bustamante-Munguira E, Fernández N, Crespo MS. Fernández JJ, et al. Genes Immun. 2024 Feb;25(1):43-54. doi: 10.1038/s41435-023-00243-6. Epub 2023 Dec 25. Genes Immun. 2024. PMID: 38146001
318 results