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Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS. Acin-Perez R, et al. Among authors: fernandez del rio l. EMBO J. 2023 May 15;42(10):e111699. doi: 10.15252/embj.2022111699. Epub 2023 Mar 13. EMBO J. 2023. PMID: 36912136 Free PMC article.
Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q.
Ayer A, Fazakerley DJ, Suarna C, Maghzal GJ, Sheipouri D, Lee KJ, Bradley MC, Fernández-Del-Rio L, Tumanov S, Kong SM, van der Veen JN, Yang A, Ho JWK, Clarke SG, James DE, Dawes IW, Vance DE, Clarke CF, Jacobs RL, Stocker R. Ayer A, et al. Among authors: fernandez del rio l. Redox Biol. 2021 Oct;46:102127. doi: 10.1016/j.redox.2021.102127. Epub 2021 Sep 8. Redox Biol. 2021. PMID: 34521065 Free PMC article.
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment.
Widmeier E, Yu S, Nag A, Chung YW, Nakayama M, Fernández-Del-Río L, Hugo H, Schapiro D, Buerger F, Choi WI, Helmstädter M, Kim JW, Ryu JH, Lee MG, Clarke CF, Hildebrandt F, Gee HY. Widmeier E, et al. Among authors: fernandez del rio l. J Am Soc Nephrol. 2020 Jun;31(6):1191-1211. doi: 10.1681/ASN.2019070756. Epub 2020 May 7. J Am Soc Nephrol. 2020. PMID: 32381600 Free PMC article.
18 results