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Page 1
Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease.
Smyth LJ, Dahlström EH, Syreeni A, Kerr K, Kilner J, Doyle R, Brennan E, Nair V, Fermin D, Nelson RG, Looker HC, Wooster C, Andrews D, Anderson K, McKay GJ, Cole JB, Salem RM, Conlon PJ, Kretzler M, Hirschhorn JN, Sadlier D, Godson C, Florez JC; GENIE consortium; Forsblom C, Maxwell AP, Groop PH, Sandholm N, McKnight AJ. Smyth LJ, et al. Among authors: fermin d. Nat Commun. 2022 Dec 22;13(1):7891. doi: 10.1038/s41467-022-34963-6. Nat Commun. 2022. PMID: 36550108 Free PMC article.
Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease.
Liu J, Nair V, Zhao YY, Chang DY, Limonte C, Bansal N, Fermin D, Eichinger F, Tanner EC, Bellovich KA, Steigerwalt S, Bhat Z, Hawkins JJ, Subramanian L, Rosas SE, Sedor JR, Vasquez MA, Waikar SS, Bitzer M, Pennathur S, Brosius FC, De Boer I, Chen M, Kretzler M, Ju W; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group. Liu J, et al. Among authors: fermin d. Diabetes. 2022 Dec 1;71(12):2664-2676. doi: 10.2337/db22-0169. Diabetes. 2022. PMID: 36331122 Free PMC article.
Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy.
Liu S, Zhao Y, Lu S, Zhang T, Lindenmeyer MT, Nair V, Gies SE, Wu G, Nelson RG, Czogalla J, Aypek H, Zielinski S, Liao Z, Schaper M, Fermin D, Cohen CD, Delic D, Krebs CF, Grahammer F, Wiech T, Kretzler M, Meyer-Schwesinger C, Bonn S, Huber TB. Liu S, et al. Among authors: fermin d. Genome Med. 2023 Jan 10;15(1):2. doi: 10.1186/s13073-022-01145-4. Genome Med. 2023. PMID: 36627643 Free PMC article.
SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes.
Schaub JA, AlAkwaa FM, McCown PJ, Naik AS, Nair V, Eddy S, Menon R, Otto EA, Demeke D, Hartman J, Fermin D, O'Connor CL, Subramanian L, Bitzer M, Harned R, Ladd P, Pyle L, Pennathur S, Inoki K, Hodgin JB, Brosius FC 3rd, Nelson RG, Kretzler M, Bjornstad P. Schaub JA, et al. Among authors: fermin d. J Clin Invest. 2023 Mar 1;133(5):e164486. doi: 10.1172/JCI164486. J Clin Invest. 2023. PMID: 36637914 Free PMC article.
Unbiased kidney-centric molecular categorization of chronic kidney disease as a step towards precision medicine.
Reznichenko A, Nair V, Eddy S, Fermin D, Tomilo M, Slidel T, Ju W, Henry I, Badal SS, Wesley JD, Liles JT, Moosmang S, Williams JM, Quinn CM, Bitzer M, Hodgin JB, Barisoni L, Karihaloo A, Breyer MD, Duffin KL, Patel UD, Magnone MC, Bhat R, Kretzler M. Reznichenko A, et al. Among authors: fermin d. Kidney Int. 2024 Jan 27:S0085-2538(24)00068-1. doi: 10.1016/j.kint.2024.01.012. Online ahead of print. Kidney Int. 2024. PMID: 38286178 Free article.
A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental glomerulosclerosis.
McNulty MT, Fermin D, Eichinger F, Jang D, Kretzler M, Burtt NP, Pollak MR, Flannick J, Weins A, Friedman DJ; Nephrotic Syndrome Study Network (NEPTUNE); Sampson MG. McNulty MT, et al. Among authors: fermin d. Kidney Int. 2022 Jul;102(1):136-148. doi: 10.1016/j.kint.2021.10.041. Epub 2021 Dec 18. Kidney Int. 2022. PMID: 34929253 Free PMC article.
Rationale and design of the Nephrotic Syndrome Study Network (NEPTUNE) Match in glomerular diseases: designing the right trial for the right patient, today.
Trachtman H, Desmond H, Williams AL, Mariani LH, Eddy S, Ju W, Barisoni L, Ascani HK, Uhlmann WR, Spino C, Holzman LB, Sedor JR, Gadegbeku C, Subramanian L, Lienczewski CC, Manieri T, Roberts SJ, Gipson DS, Kretzler M; NEPTUNE investigators. Trachtman H, et al. Kidney Int. 2024 Feb;105(2):218-230. doi: 10.1016/j.kint.2023.11.018. Kidney Int. 2024. PMID: 38245210 Free PMC article.
Kidney Biopsy Features Most Predictive of Clinical Outcomes in the Spectrum of Minimal Change Disease and Focal Segmental Glomerulosclerosis.
Zee J, Liu Q, Smith AR, Hodgin JB, Rosenberg A, Gillespie BW, Holzman LB, Barisoni L, Mariani LH; Nephrotic Syndrome Study Network (NEPTUNE); NEPTUNE Members. Zee J, et al. J Am Soc Nephrol. 2022 Jul;33(7):1411-1426. doi: 10.1681/ASN.2021101396. Epub 2022 May 17. J Am Soc Nephrol. 2022. PMID: 35581011 Free PMC article.
Pediatric contributions and lessons learned from the NEPTUNE cohort study.
Modi ZJ, Zhai Y, Yee J, Desmond H, Hao W, Sampson MG, Sethna CB, Wang CS, Gipson DS, Trachtman H, Kretzler M; NEPTUNE investigators. Modi ZJ, et al. Pediatr Nephrol. 2024 Jan 18. doi: 10.1007/s00467-023-06256-7. Online ahead of print. Pediatr Nephrol. 2024. PMID: 38233720 Review.
Quantification of Glomerular Structural Lesions: Associations With Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome.
Hodgin JB, Mariani LH, Zee J, Liu Q, Smith AR, Eddy S, Hartman J, Hamidi H, Gaut JP, Palmer MB, Nast CC, Chang A, Hewitt S, Gillespie BW, Kretzler M, Holzman LB, Barisoni L; Nephrotic Syndrome Study Network (NEPTUNE). Hodgin JB, et al. Am J Kidney Dis. 2022 Jun;79(6):807-819.e1. doi: 10.1053/j.ajkd.2021.10.004. Epub 2021 Dec 3. Am J Kidney Dis. 2022. PMID: 34864148 Free PMC article.
122 results