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Both RyRs and TPCs are required for NAADP-induced intracellular Ca²⁺ release.
Gerasimenko JV, Charlesworth RM, Sherwood MW, Ferdek PE, Mikoshiba K, Parrington J, Petersen OH, Gerasimenko OV. Gerasimenko JV, et al. Among authors: ferdek pe. Cell Calcium. 2015 Sep;58(3):237-45. doi: 10.1016/j.ceca.2015.05.005. Epub 2015 Jun 10. Cell Calcium. 2015. PMID: 26100948 Free PMC article.
Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy.
Gerasimenko JV, Gryshchenko O, Ferdek PE, Stapleton E, Hébert TO, Bychkova S, Peng S, Begg M, Gerasimenko OV, Petersen OH. Gerasimenko JV, et al. Among authors: ferdek pe. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13186-91. doi: 10.1073/pnas.1300910110. Epub 2013 Jul 22. Proc Natl Acad Sci U S A. 2013. PMID: 23878235 Free PMC article.
ABT-199 (Venetoclax), a BH3-mimetic Bcl-2 inhibitor, does not cause Ca2+ -signalling dysregulation or toxicity in pancreatic acinar cells.
Jakubowska MA, Kerkhofs M, Martines C, Efremov DG, Gerasimenko JV, Gerasimenko OV, Petersen OH, Bultynck G, Vervliet T, Ferdek PE. Jakubowska MA, et al. Among authors: ferdek pe. Br J Pharmacol. 2019 Nov;176(22):4402-4415. doi: 10.1111/bph.14505. Epub 2018 Nov 8. Br J Pharmacol. 2019. PMID: 30266036 Free PMC article.
Activation of pancreatic stellate cells attenuates intracellular Ca2+ signals due to downregulation of TRPA1 and protects against cell death induced by alcohol metabolites.
Kusiak AA, Jakubowska MA, Stopa KB, Zhang X, Huang W, Gerasimenko JV, Gerasimenko OV, Sutton R, Petersen OH, Ferdek PE. Kusiak AA, et al. Among authors: ferdek pe. Cell Death Dis. 2022 Aug 29;13(8):744. doi: 10.1038/s41419-022-05186-w. Cell Death Dis. 2022. PMID: 36038551 Free PMC article.
30 results