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Chalcone-based carbamates for Alzheimer's disease treatment.
Rampa A, Montanari S, Pruccoli L, Bartolini M, Falchi F, Feoli A, Cavalli A, Belluti F, Gobbi S, Tarozzi A, Bisi A. Rampa A, et al. Among authors: feoli a. Future Med Chem. 2017 May;9(8):749-764. doi: 10.4155/fmc-2017-0029. Epub 2017 May 12. Future Med Chem. 2017. PMID: 28498775
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.
Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML. Gandini A, et al. Among authors: feoli a. J Med Chem. 2018 Sep 13;61(17):7640-7656. doi: 10.1021/acs.jmedchem.8b00610. Epub 2018 Aug 24. J Med Chem. 2018. PMID: 30078314
Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure.
Milite C, Feoli A, Horton JR, Rescigno D, Cipriano A, Pisapia V, Viviano M, Pepe G, Amendola G, Novellino E, Cosconati S, Cheng X, Castellano S, Sbardella G. Milite C, et al. Among authors: feoli a. J Med Chem. 2019 Mar 14;62(5):2666-2689. doi: 10.1021/acs.jmedchem.8b02008. Epub 2019 Feb 26. J Med Chem. 2019. PMID: 30753076 Free PMC article.
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies.
Milite C, Amendola G, Nocentini A, Bua S, Cipriano A, Barresi E, Feoli A, Novellino E, Da Settimo F, Supuran CT, Castellano S, Cosconati S, Taliani S. Milite C, et al. Among authors: feoli a. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1697-1710. doi: 10.1080/14756366.2019.1666836. J Enzyme Inhib Med Chem. 2019. PMID: 31537132 Free PMC article.
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.
Fiorentino F, Sementilli S, Menna M, Turrisi F, Tomassi S, Pellegrini FR, Iuzzolino A, D'Acunzo F, Feoli A, Wapenaar H, Taraglio S, Fraschetti C, Del Bufalo D, Sbardella G, Dekker FJ, Paiardini A, Trisciuoglio D, Mai A, Rotili D. Fiorentino F, et al. Among authors: feoli a. J Med Chem. 2023 May 25;66(10):6591-6616. doi: 10.1021/acs.jmedchem.2c01937. Epub 2023 May 8. J Med Chem. 2023. PMID: 37155735 Free PMC article.
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor.
Feoli A, Iannelli G, Cipriano A, Milite C, Shen L, Wang Z, Hadjikyriacou A, Lowe TL, Safaeipour C, Viviano M, Sarno G, Morretta E, Monti MC, Yang Y, Clarke SG, Cosconati S, Castellano S, Sbardella G. Feoli A, et al. J Med Chem. 2023 Oct 12;66(19):13665-13683. doi: 10.1021/acs.jmedchem.3c01030. Epub 2023 Aug 10. J Med Chem. 2023. PMID: 37560786 Free PMC article.
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