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Quantifying the impact of transporters on cellular drug permeability.
Trends Pharmacol Sci. 2015 May;36(5):255-62. doi: 10.1016/j.tips.2015.02.009. Epub 2015 Mar 19.
Trends Pharmacol Sci. 2015.
PMID: 25799456
Review.
Addendum to 'Quantifying the impact of transporters on cellular drug permeability'.
Matsson P, Fenu LA, Lundquist P, Wiśniewski JR, Kansy M, Artursson P.
Matsson P, et al. Among authors: fenu la.
Trends Pharmacol Sci. 2015 Sep;36(9):559. doi: 10.1016/j.tips.2015.06.009. Epub 2015 Jul 24.
Trends Pharmacol Sci. 2015.
PMID: 26216247
No abstract available.
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Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry.
Sinha VK, Vaarties K, De Buck SS, Fenu LA, Nijsen M, Gilissen RA, Sanderson W, Van Uytsel K, Hoeben E, Van Peer A, Mackie CE, Smit JW.
Sinha VK, et al. Among authors: fenu la.
Clin Pharmacokinet. 2011 May;50(5):307-18. doi: 10.2165/11539250-000000000-00000.
Clin Pharmacokinet. 2011.
PMID: 21456631
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Cardio-vascular safety beyond hERG: in silico modelling of a guinea pig right atrium assay.
Fenu LA, Teisman A, De Buck SS, Sinha VK, Gilissen RA, Nijsen MJ, Mackie CE, Sanderson WE.
Fenu LA, et al.
J Comput Aided Mol Des. 2009 Dec;23(12):883-95. doi: 10.1007/s10822-009-9306-z. Epub 2009 Nov 5.
J Comput Aided Mol Des. 2009.
PMID: 19890608
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Predicting oral clearance in humans: how close can we get with allometry?
Sinha VK, De Buck SS, Fenu LA, Smit JW, Nijsen M, Gilissen RA, Van Peer A, Lavrijsen K, Mackie CE.
Sinha VK, et al. Among authors: fenu la.
Clin Pharmacokinet. 2008;47(1):35-45. doi: 10.2165/00003088-200847010-00004.
Clin Pharmacokinet. 2008.
PMID: 18076217
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Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs.
De Buck SS, Sinha VK, Fenu LA, Nijsen MJ, Mackie CE, Gilissen RA.
De Buck SS, et al. Among authors: fenu la.
Drug Metab Dispos. 2007 Oct;35(10):1766-80. doi: 10.1124/dmd.107.015644. Epub 2007 Jul 9.
Drug Metab Dispos. 2007.
PMID: 17620347
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The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse compounds in rat using mechanism-based absorption, distribution, and metabolism prediction tools.
De Buck SS, Sinha VK, Fenu LA, Gilissen RA, Mackie CE, Nijsen MJ.
De Buck SS, et al. Among authors: fenu la.
Drug Metab Dispos. 2007 Apr;35(4):649-59. doi: 10.1124/dmd.106.014027. Epub 2007 Jan 31.
Drug Metab Dispos. 2007.
PMID: 17267621
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Understanding diffusion in confined systems: methane in a ZK4 molecular sieve. A molecular dynamics simulation study.
Demontis P, Fenu LA, Suffritti GB.
Demontis P, et al. Among authors: fenu la.
J Phys Chem B. 2005 Sep 29;109(38):18081-7. doi: 10.1021/jp052597g.
J Phys Chem B. 2005.
PMID: 16853322
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