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Pan-cancer deconvolution of tumour composition using DNA methylation.
Chakravarthy A, Furness A, Joshi K, Ghorani E, Ford K, Ward MJ, King EV, Lechner M, Marafioti T, Quezada SA, Thomas GJ, Feber A, Fenton TR. Chakravarthy A, et al. Among authors: fenton tr. Nat Commun. 2018 Aug 13;9(1):3220. doi: 10.1038/s41467-018-05570-1. Nat Commun. 2018. PMID: 30104673 Free PMC article.
NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors.
Ford K, Hanley CJ, Mellone M, Szyndralewiez C, Heitz F, Wiesel P, Wood O, Machado M, Lopez MA, Ganesan AP, Wang C, Chakravarthy A, Fenton TR, King EV, Vijayanand P, Ottensmeier CH, Al-Shamkhani A, Savelyeva N, Thomas GJ. Ford K, et al. Among authors: fenton tr. Cancer Res. 2020 May 1;80(9):1846-1860. doi: 10.1158/0008-5472.CAN-19-3158. Epub 2020 Mar 2. Cancer Res. 2020. PMID: 32122909 Free PMC article.
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Chakravarthy A, Reddin I, Henderson S, Dong C, Kirkwood N, Jeyakumar M, Rodriguez DR, Martinez NG, McDermott J, Su X, Egawa N, Fjeldbo CS, Skingen VE, Lyng H, Halle MK, Krakstad C, Soleiman A, Sprung S, Lechner M, Ellis PJI, Wass M, Michaelis M, Fiegl H, Salvesen H, Thomas GJ, Doorbar J, Chester K, Feber A, Fenton TR. Chakravarthy A, et al. Among authors: fenton tr. Nat Commun. 2022 Oct 7;13(1):5818. doi: 10.1038/s41467-022-33544-x. Nat Commun. 2022. PMID: 36207323 Free PMC article.
Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.
Chakravarthy A, Henderson S, Thirdborough SM, Ottensmeier CH, Su X, Lechner M, Feber A, Thomas GJ, Fenton TR. Chakravarthy A, et al. Among authors: fenton tr. J Clin Oncol. 2016 Dec;34(34):4132-4141. doi: 10.1200/JCO.2016.68.2955. Epub 2016 Oct 31. J Clin Oncol. 2016. PMID: 27863190 Free PMC article.
Frequent HPV-independent p16/INK4A overexpression in head and neck cancer.
Lechner M, Chakravarthy AR, Walter V, Masterson L, Feber A, Jay A, Weinberger PM, McIndoe RA, Forde CT, Chester K, Kalavrezos N, O'Flynn P, Forster M, Jones TM, Vaz FM, Hayes DN, Fenton TR. Lechner M, et al. Among authors: fenton tr. Oral Oncol. 2018 Aug;83:32-37. doi: 10.1016/j.oraloncology.2018.06.006. Epub 2018 Jun 9. Oral Oncol. 2018. PMID: 30098776
181 results