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APC Mutation Marks an Aggressive Subtype of BRAF Mutant Colorectal Cancers.
Fennell LJ, Kane A, Liu C, McKeone D, Fernando W, Su C, Bond C, Jamieson S, Dumenil T, Patch AM, Kazakoff SH, Pearson JV, Waddell N, Leggett B, Whitehall VLJ. Fennell LJ, et al. Cancers (Basel). 2020 May 6;12(5):1171. doi: 10.3390/cancers12051171. Cancers (Basel). 2020. PMID: 32384699 Free PMC article.
The role of APC in WNT pathway activation in serrated neoplasia.
Borowsky J, Dumenil T, Bettington M, Pearson SA, Bond C, Fennell L, Liu C, McKeone D, Rosty C, Brown I, Walker N, Leggett B, Whitehall V. Borowsky J, et al. Mod Pathol. 2018 Mar;31(3):495-504. doi: 10.1038/modpathol.2017.150. Epub 2017 Nov 17. Mod Pathol. 2018. PMID: 29148535 Free article.
Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia.
Bond CE, Liu C, Kawamata F, McKeone DM, Fernando W, Jamieson S, Pearson SA, Kane A, Woods SL, Lannagan TRM, Somashekar R, Lee Y, Dumenil T, Hartel G, Spring KJ, Borowsky J, Fennell L, Bettington M, Lee J, Worthley DL, Leggett BA, Whitehall VLJ. Bond CE, et al. Epigenetics. 2018;13(1):40-48. doi: 10.1080/15592294.2017.1411446. Epub 2018 Feb 19. Epigenetics. 2018. PMID: 29235923 Free PMC article.
Copy number profiles of paired primary and metastatic colorectal cancers.
Kawamata F, Patch AM, Nones K, Bond C, McKeone D, Pearson SA, Homma S, Liu C, Fennell L, Dumenil T, Hartel G, Kobayasi N, Yokoo H, Fukai M, Nishihara H, Kamiyama T, Burge ME, Karapetis CS, Taketomi A, Leggett B, Waddell N, Whitehall V. Kawamata F, et al. Oncotarget. 2017 Dec 15;9(3):3394-3405. doi: 10.18632/oncotarget.23277. eCollection 2018 Jan 9. Oncotarget. 2017. PMID: 29423054 Free PMC article.
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL. Lannagan TRM, et al. Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17. Gut. 2019. PMID: 29666172 Free PMC article.
Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas.
Fennell L, Dumenil T, Wockner L, Hartel G, Nones K, Bond C, Borowsky J, Liu C, McKeone D, Bowdler L, Montgomery G, Klein K, Hoffmann I, Patch AM, Kazakoff S, Pearson J, Waddell N, Wirapati P, Lochhead P, Imamura Y, Ogino S, Shao R, Tejpar S, Leggett B, Whitehall V. Fennell L, et al. Cell Mol Gastroenterol Hepatol. 2019;8(2):269-290. doi: 10.1016/j.jcmgh.2019.04.002. Epub 2019 Apr 5. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30954552 Free PMC article.
Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer.
Kane AM, Fennell LJ, Liu C, Borowsky J, McKeone DM, Bond CE, Kazakoff S, Patch AM, Koufariotis LT, Pearson J, Waddell N, Leggett BA, Whitehall VLJ. Kane AM, et al. Among authors: fennell lj. Neoplasia. 2020 Feb;22(2):120-128. doi: 10.1016/j.neo.2019.12.002. Epub 2020 Jan 11. Neoplasia. 2020. PMID: 31935636 Free PMC article.
15 results