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Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.
Landge S, Mullick AB, Nagalapur K, Neres J, Subbulakshmi V, Murugan K, Ghosh A, Sadler C, Fellows MD, Humnabadkar V, Mahadevaswamy J, Vachaspati P, Sharma S, Kaur P, Mallya M, Rudrapatna S, Awasthy D, Sambandamurthy VK, Pojer F, Cole ST, Balganesh TS, Ugarkar BG, Balasubramanian V, Bandodkar BS, Panda M, Ramachandran V. Landge S, et al. Among authors: fellows md. Bioorg Med Chem. 2015 Dec 15;23(24):7694-710. doi: 10.1016/j.bmc.2015.11.017. Epub 2015 Nov 18. Bioorg Med Chem. 2015. PMID: 26643218
Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity.
Landge S, Ramachandran V, Kumar A, Neres J, Murugan K, Sadler C, Fellows MD, Humnabadkar V, Vachaspati P, Raichurkar A, Sharma S, Ravishankar S, Guptha S, Sambandamurthy VK, Balganesh TS, Ugarkar BG, Balasubramanian V, Bandodkar BS, Panda M. Landge S, et al. Among authors: fellows md. ChemMedChem. 2016 Feb 4;11(3):331-9. doi: 10.1002/cmdc.201500462. Epub 2016 Jan 11. ChemMedChem. 2016. PMID: 26751718
Etoposide, cadmium chloride, benzo[a]pyrene, cyclophosphamide and colchicine tested in the in vitro mammalian cell micronucleus test (MNvit) in the presence and absence of cytokinesis block using L5178Y mouse lymphoma cells and 2-aminoanthracene tested in MNvit in the absence of cytokinesis block using TK6 cells at AstraZeneca UK, in support of OECD draft Test Guideline 487.
Fellows MD, O'Donovan MR. Fellows MD, et al. Mutat Res. 2010 Oct 29;702(2):163-70. doi: 10.1016/j.mrgentox.2009.09.003. Epub 2009 Sep 15. Mutat Res. 2010. PMID: 19761867
Standardized cell sources and recommendations for good cell culture practices in genotoxicity testing.
Lorge E, Moore MM, Clements J, O'Donovan M, Fellows MD, Honma M, Kohara A, Galloway S, Armstrong MJ, Thybaud V, Gollapudi B, Aardema MJ, Tanir JY. Lorge E, et al. Among authors: fellows md. Mutat Res Genet Toxicol Environ Mutagen. 2016 Oct;809:1-15. doi: 10.1016/j.mrgentox.2016.08.001. Epub 2016 Aug 3. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27692294 Free article.
39 results