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Differential Effector Engagement by Oncogenic KRAS.
Yuan TL, Amzallag A, Bagni R, Yi M, Afghani S, Burgan W, Fer N, Strathern LA, Powell K, Smith B, Waters AM, Drubin D, Thomson T, Liao R, Greninger P, Stein GT, Murchie E, Cortez E, Egan RK, Procter L, Bess M, Cheng KT, Lee CS, Lee LC, Fellmann C, Stephens R, Luo J, Lowe SW, Benes CH, McCormick F. Yuan TL, et al. Among authors: fellmann c. Cell Rep. 2018 Feb 13;22(7):1889-1902. doi: 10.1016/j.celrep.2018.01.051. Cell Rep. 2018. PMID: 29444439 Free PMC article.
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.
Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, Lowe SW. Zuber J, et al. Among authors: fellmann c. Genes Dev. 2011 Aug 1;25(15):1628-40. doi: 10.1101/gad.17269211. Genes Dev. 2011. PMID: 21828272 Free PMC article.
A pipeline for the generation of shRNA transgenic mice.
Dow LE, Premsrirut PK, Zuber J, Fellmann C, McJunkin K, Miething C, Park Y, Dickins RA, Hannon GJ, Lowe SW. Dow LE, et al. Among authors: fellmann c. Nat Protoc. 2012 Feb 2;7(2):374-93. doi: 10.1038/nprot.2011.446. Nat Protoc. 2012. PMID: 22301776 Free PMC article.
Stable RNA interference rules for silencing.
Fellmann C, Lowe SW. Fellmann C, et al. Nat Cell Biol. 2014 Jan;16(1):10-8. doi: 10.1038/ncb2895. Nat Cell Biol. 2014. PMID: 24366030 Free PMC article. Review.
Development of siRNA payloads to target KRAS-mutant cancer.
Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW. Yuan TL, et al. Among authors: fellmann c. Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100204 Free PMC article.
Prediction of potent shRNAs with a sequential classification algorithm.
Pelossof R, Fairchild L, Huang CH, Widmer C, Sreedharan VT, Sinha N, Lai DY, Guan Y, Premsrirut PK, Tschaharganeh DF, Hoffmann T, Thapar V, Xiang Q, Garippa RJ, Rätsch G, Zuber J, Lowe SW, Leslie CS, Fellmann C. Pelossof R, et al. Among authors: fellmann c. Nat Biotechnol. 2017 Apr;35(4):350-353. doi: 10.1038/nbt.3807. Epub 2017 Mar 6. Nat Biotechnol. 2017. PMID: 28263295 Free PMC article.
40 results