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Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth.
Delle Donne R, Iannucci R, Rinaldi L, Roberto L, Oliva MA, Senatore E, Borzacchiello D, Lignitto L, Giurato G, Rizzo F, Sellitto A, Chiuso F, Castaldo S, Scala G, Campani V, Nele V, De Rosa G, D'Ambrosio C, Garbi C, Scaloni A, Weisz A, Ambrosino C, Arcella A, Feliciello A. Delle Donne R, et al. Among authors: feliciello a. Commun Biol. 2022 Aug 2;5(1):780. doi: 10.1038/s42003-022-03639-8. Commun Biol. 2022. PMID: 35918402 Free PMC article.
Mitochondrial AKAP121 links cAMP and src signaling to oxidative metabolism.
Livigni A, Scorziello A, Agnese S, Adornetto A, Carlucci A, Garbi C, Castaldo I, Annunziato L, Avvedimento EV, Feliciello A. Livigni A, et al. Among authors: feliciello a. Mol Biol Cell. 2006 Jan;17(1):263-71. doi: 10.1091/mbc.e05-09-0827. Epub 2005 Oct 26. Mol Biol Cell. 2006. PMID: 16251349 Free PMC article.
AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress.
Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro L, Del Gatto A, Saviano M, Garbi C, Carangi R, Di Lorenzo E, Donato G, Indolfi C, Avvedimento VE, Chiariello M. Perrino C, et al. Among authors: feliciello a. Cardiovasc Res. 2010 Oct 1;88(1):101-10. doi: 10.1093/cvr/cvq155. Epub 2010 May 28. Cardiovasc Res. 2010. PMID: 20511238
PTPD1 supports receptor stability and mitogenic signaling in bladder cancer cells.
Carlucci A, Porpora M, Garbi C, Galgani M, Santoriello M, Mascolo M, di Lorenzo D, Altieri V, Quarto M, Terracciano L, Gottesman ME, Insabato L, Feliciello A. Carlucci A, et al. Among authors: feliciello a. J Biol Chem. 2010 Dec 10;285(50):39260-70. doi: 10.1074/jbc.M110.174706. Epub 2010 Oct 5. J Biol Chem. 2010. PMID: 20923765 Free PMC article.
Control of PKA stability and signalling by the RING ligase praja2.
Lignitto L, Carlucci A, Sepe M, Stefan E, Cuomo O, Nisticò R, Scorziello A, Savoia C, Garbi C, Annunziato L, Feliciello A. Lignitto L, et al. Among authors: feliciello a. Nat Cell Biol. 2011 Apr;13(4):412-22. doi: 10.1038/ncb2209. Epub 2011 Mar 20. Nat Cell Biol. 2011. PMID: 21423175
146 results