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CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation.
Eitler J, Rackwitz W, Wotschel N, Gudipati V, Murali Shankar N, Sidorenkova A, Huppa JB, Ortiz-Montero P, Opitz C, Künzel SR, Michen S, Temme A, Loureiro LR, Feldmann A, Bachmann M, Boissel L, Klingemann H, Wels WS, Tonn T. Eitler J, et al. Among authors: feldmann a. J Immunother Cancer. 2024 Feb 27;12(2):e008155. doi: 10.1136/jitc-2023-008155. J Immunother Cancer. 2024. PMID: 38417916 Free PMC article.
Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T-cell function while promoting a senescence-associated phenotype.
Towers R, Trombello L, Fusenig M, Tunger A, Baumann AL, Savoldelli R, Wehner R, Fasslrinner F, Arndt C, Dazzi F, Von Bonin M, Feldmann A, Bachmann MP, Wobus M, Schmitz M, Bornhäuser M. Towers R, et al. Among authors: feldmann a. Cancer Immunol Immunother. 2024 Jan 17;73(1):8. doi: 10.1007/s00262-023-03594-1. Cancer Immunol Immunother. 2024. PMID: 38231344 Free PMC article.
Targeting colorectal cancer cells using AND-gated adaptor RevCAR T-cells.
Soto KEG, Loureiro LR, Bartsch T, Arndt C, Kegler A, Mitwasi N, Drewitz L, Hoffmann L, Saleh HA, Crespo E, Mehnert M, Daglar C, Abken H, Momburg F, Bachmann M, Feldmann A. Soto KEG, et al. Among authors: feldmann a. Front Immunol. 2023 Dec 15;14:1302354. doi: 10.3389/fimmu.2023.1302354. eCollection 2023. Front Immunol. 2023. PMID: 38169746 Free PMC article.
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
Funk MC, Gleixner JG, Heigwer F, Vonficht D, Valentini E, Aydin Z, Tonin E, Del Prete S, Mahara S, Throm Y, Hetzer J, Heide D, Stegle O, Odom DT, Feldmann A, Haas S, Heikenwalder M, Boutros M. Funk MC, et al. Among authors: feldmann a. Dev Cell. 2023 Dec 18;58(24):2914-2929.e7. doi: 10.1016/j.devcel.2023.11.013. Dev Cell. 2023. PMID: 38113852 Free article.
Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment.
Loureiro LR, Hoffmann L, Neuber C, Rupp L, Arndt C, Kegler A, Kubeil M, Hagemeyer CE, Stephan H, Schmitz M, Feldmann A, Bachmann M. Loureiro LR, et al. Among authors: feldmann a. J Exp Clin Cancer Res. 2023 Dec 15;42(1):341. doi: 10.1186/s13046-023-02912-w. J Exp Clin Cancer Res. 2023. PMID: 38102692 Free PMC article.
170 results