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The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients.
Marini MA, Frontoni S, Mineo D, Bracaglia D, Cardellini M, De Nicolais P, Baroni A, D'Alfonso R, Perna M, Lauro D, Federici M, Gambardella S, Lauro R, Sesti G. Marini MA, et al. Among authors: federici m. J Clin Endocrinol Metab. 2003 Jul;88(7):3368-71. doi: 10.1210/jc.2002-021716. J Clin Endocrinol Metab. 2003. PMID: 12843189
Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.
D'Alessandris C, Andreozzi F, Federici M, Cardellini M, Brunetti A, Ranalli M, Del Guerra S, Lauro D, Del Prato S, Marchetti P, Lauro R, Sesti G. D'Alessandris C, et al. Among authors: federici m. FASEB J. 2004 Jun;18(9):959-61. doi: 10.1096/fj.03-0725fje. Epub 2004 Apr 1. FASEB J. 2004. PMID: 15059979
Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha.
Federici M, Hribal ML, Menghini R, Kanno H, Marchetti V, Porzio O, Sunnarborg SW, Rizza S, Serino M, Cunsolo V, Lauro D, Mauriello A, Smookler DS, Sbraccia P, Sesti G, Lee DC, Khokha R, Accili D, Lauro R. Federici M, et al. J Clin Invest. 2005 Dec;115(12):3494-505. doi: 10.1172/JCI26052. Epub 2005 Nov 17. J Clin Invest. 2005. PMID: 16294222 Free PMC article.
Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients.
Cardellini M, Marini MA, Frontoni S, Hribal ML, Andreozzi F, Perticone F, Federici M, Lauro D, Sesti G. Cardellini M, et al. Among authors: federici m. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E347-52. doi: 10.1152/ajpendo.00291.2006. Epub 2006 Sep 12. Am J Physiol Endocrinol Metab. 2007. PMID: 16968812 Free article.
448 results