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Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Cai Y, Fedeles SV, Dong K, Anyatonwu G, Onoe T, Mitobe M, Gao JD, Okuhara D, Tian X, Gallagher AR, Tang Z, Xie X, Lalioti MD, Lee AH, Ehrlich BE, Somlo S. Cai Y, et al. Among authors: fedeles sv. J Clin Invest. 2014 Dec;124(12):5129-44. doi: 10.1172/JCI67273. Epub 2014 Nov 3. J Clin Invest. 2014. PMID: 25365220 Free PMC article.
Steviol retards renal cyst growth through reduction of CFTR expression and inhibition of epithelial cell proliferation in a mouse model of polycystic kidney disease.
Yuajit C, Muanprasat C, Gallagher AR, Fedeles SV, Kittayaruksakul S, Homvisasevongsa S, Somlo S, Chatsudthipong V. Yuajit C, et al. Among authors: fedeles sv. Biochem Pharmacol. 2014 Apr 1;88(3):412-21. doi: 10.1016/j.bcp.2014.01.038. Epub 2014 Feb 8. Biochem Pharmacol. 2014. PMID: 24518257
Is it Time to Fold the Cysts Away?
Krappitz M, Gallagher AR, Fedeles S. Krappitz M, et al. Trends Mol Med. 2016 Dec;22(12):997-999. doi: 10.1016/j.molmed.2016.10.001. Epub 2016 Oct 25. Trends Mol Med. 2016. PMID: 27793600
Isolated polycystic liver disease genes define effectors of polycystin-1 function.
Besse W, Dong K, Choi J, Punia S, Fedeles SV, Choi M, Gallagher AR, Huang EB, Gulati A, Knight J, Mane S, Tahvanainen E, Tahvanainen P, Sanna-Cherchi S, Lifton RP, Watnick T, Pei YP, Torres VE, Somlo S. Besse W, et al. Among authors: fedeles sv. J Clin Invest. 2017 May 1;127(5):1772-1785. doi: 10.1172/JCI90129. Epub 2017 Apr 4. J Clin Invest. 2017. PMID: 28375157 Free PMC article.
Isolated polycystic liver disease genes define effectors of polycystin-1 function.
Besse W, Dong K, Choi J, Punia S, Fedeles SV, Choi M, Gallagher AR, Huang EB, Gulati A, Knight J, Mane S, Tahvanainen E, Tahvanainen P, Sanna-Cherchi S, Lifton RP, Watnick T, Pei YP, Torres VE, Somlo S. Besse W, et al. Among authors: fedeles sv. J Clin Invest. 2017 Sep 1;127(9):3558. doi: 10.1172/JCI96729. Epub 2017 Sep 1. J Clin Invest. 2017. PMID: 28862642 Free PMC article.
19 results