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Blocking Src-PSD-95 interaction rescues glutamatergic signaling dysregulation in schizophrenia.
Featherstone RE, Li H, Sengar A, Borgmann-Winter KE, Melnychenko O, Crown LM, Gifford RL, Amirfathi F, Banerjee A, Parekh K, Heller M, Zhang W, Marc AD, Salter MW, Siegel SJ, Hahn CG. Featherstone RE, et al. bioRxiv [Preprint]. 2024 Mar 8:2024.03.08.584132. doi: 10.1101/2024.03.08.584132. bioRxiv. 2024. PMID: 38496466 Free PMC article. Preprint.
Calcium/calmodulin-dependent protein kinase IIα heterozygous knockout mice show electroencephalogram and behavioral changes characteristic of a subpopulation of schizophrenia and intellectual impairment.
Featherstone RE, Shimada T, Crown LM, Melnychenko O, Yi J, Matsumoto M, Tajinda K, Mihara T, Adachi M, Siegel SJ. Featherstone RE, et al. Neuroscience. 2022 Sep 1;499:104-117. doi: 10.1016/j.neuroscience.2022.07.023. Epub 2022 Jul 25. Neuroscience. 2022. PMID: 35901933
Src deficient mice demonstrate behavioral and electrophysiological alterations relevant to psychiatric and developmental disease.
Ward KR, Featherstone RE, Naschek MJ, Melnychenko O, Banerjee A, Yi J, Gifford RL, Borgmann-Winter KE, Salter MW, Hahn CG, Siegel SJ. Ward KR, et al. Among authors: featherstone re. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jul 13;93:84-92. doi: 10.1016/j.pnpbp.2019.02.017. Epub 2019 Feb 28. Prog Neuropsychopharmacol Biol Psychiatry. 2019. PMID: 30826459
Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models.
Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM. Choi CH, et al. Among authors: featherstone re. Front Behav Neurosci. 2016 Jun 30;10:136. doi: 10.3389/fnbeh.2016.00136. eCollection 2016. Front Behav Neurosci. 2016. PMID: 27445731 Free PMC article.
36 results