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Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA. Öhlund D, et al. Among authors: fearon dt. J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23. J Exp Med. 2017. PMID: 28232471 Free PMC article.
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.
Roberts EW, Deonarine A, Jones JO, Denton AE, Feig C, Lyons SK, Espeli M, Kraman M, McKenna B, Wells RJ, Zhao Q, Caballero OL, Larder R, Coll AP, O'Rahilly S, Brindle KM, Teichmann SA, Tuveson DA, Fearon DT. Roberts EW, et al. Among authors: fearon dt. J Exp Med. 2013 Jun 3;210(6):1137-51. doi: 10.1084/jem.20122344. Epub 2013 May 27. J Exp Med. 2013. PMID: 23712428 Free PMC article.
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
Feig C, Jones JO, Kraman M, Wells RJ, Deonarine A, Chan DS, Connell CM, Roberts EW, Zhao Q, Caballero OL, Teichmann SA, Janowitz T, Jodrell DI, Tuveson DA, Fearon DT. Feig C, et al. Among authors: fearon dt. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20212-7. doi: 10.1073/pnas.1320318110. Epub 2013 Nov 25. Proc Natl Acad Sci U S A. 2013. PMID: 24277834 Free PMC article.
Stromal Cells in the Tumor Microenvironment.
Denton AE, Roberts EW, Fearon DT. Denton AE, et al. Among authors: fearon dt. Adv Exp Med Biol. 2018;1060:99-114. doi: 10.1007/978-3-319-78127-3_6. Adv Exp Med Biol. 2018. PMID: 30155624 Review.
Cancer cell CCR2 orchestrates suppression of the adaptive immune response.
Fein MR, He XY, Almeida AS, Bružas E, Pommier A, Yan R, Eberhardt A, Fearon DT, Van Aelst L, Wilkinson JE, Dos Santos CO, Egeblad M. Fein MR, et al. Among authors: fearon dt. J Exp Med. 2020 Oct 5;217(10):e20181551. doi: 10.1084/jem.20181551. J Exp Med. 2020. PMID: 32667673 Free PMC article.
229 results