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HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model.
Melo E, Oertle P, Trepp C, Meistermann H, Burgoyne T, Sborgi L, Cabrera AC, Chen CY, Hoflack JC, Kam-Thong T, Schmucki R, Badi L, Flint N, Ghiani ZE, Delobel F, Stucki C, Gromo G, Einhaus A, Hornsperger B, Golling S, Siebourg-Polster J, Gerber F, Bohrmann B, Futter C, Dunkley T, Hiller S, Schilling O, Enzmann V, Fauser S, Plodinec M, Iacone R. Melo E, et al. Among authors: fauser s. EBioMedicine. 2018 Jan;27:258-274. doi: 10.1016/j.ebiom.2017.12.011. Epub 2017 Dec 13. EBioMedicine. 2018. PMID: 29269042 Free PMC article.
N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration.
Chen CY, Melo E, Jakob P, Friedlein A, Elsässer B, Goettig P, Kueppers V, Delobel F, Stucki C, Dunkley T, Fauser S, Schilling O, Iacone R. Chen CY, et al. Among authors: fauser s. Matrix Biol. 2018 Sep;70:84-101. doi: 10.1016/j.matbio.2018.03.013. Epub 2018 Mar 20. Matrix Biol. 2018. PMID: 29572155 Free article.
Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.
Lorés-Motta L, van Beek AE, Willems E, Zandstra J, van Mierlo G, Einhaus A, Mary JL, Stucki C, Bakker B, Hoyng CB, Fauser S, Clark SJ, de Jonge MI, Nogoceke E, Koertvely E, Jongerius I, Kuijpers TW, den Hollander AI. Lorés-Motta L, et al. Among authors: fauser s. Am J Hum Genet. 2021 Aug 5;108(8):1367-1384. doi: 10.1016/j.ajhg.2021.06.002. Epub 2021 Jul 13. Am J Hum Genet. 2021. PMID: 34260947 Free PMC article.
The Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK Consortium.
Thee EF, Colijn JM, Cougnard-Grégoire A, Meester-Smoor MA, Verzijden T, Hoyng CB, Fauser S, Hense HW, Silva R, Creuzot-Garcher C, Ueffing M, Delcourt C, den Hollander AI, Klaver CCW; European Eye Epidemiology Consortium and EYE-RISK Project. Thee EF, et al. Among authors: fauser s. Ophthalmology. 2022 Jul;129(7):752-764. doi: 10.1016/j.ophtha.2022.02.026. Epub 2022 Mar 1. Ophthalmology. 2022. PMID: 35240203 Free article.
Allergy is a protective factor against age-related macular degeneration.
Ristau T, Ersoy L, Lechanteur Y, den Hollander AI, Daha MR, Hahn M, Hoyng CB, Fauser S. Ristau T, et al. Among authors: fauser s. Invest Ophthalmol Vis Sci. 2014 Jan 9;55(1):210-4. doi: 10.1167/iovs.13-13248. Invest Ophthalmol Vis Sci. 2014. PMID: 24235017
328 results