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2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Bernhart E, Kogelnik N, Prasch J, Gottschalk B, Goeritzer M, Depaoli MR, Reicher H, Nusshold C, Plastira I, Hammer A, Fauler G, Malli R, Graier WF, Malle E, Sattler W. Bernhart E, et al. Among authors: fauler g. Redox Biol. 2018 May;15:441-451. doi: 10.1016/j.redox.2018.01.003. Epub 2018 Jan 5. Redox Biol. 2018. PMID: 29413957 Free PMC article.
2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis.
Marsche G, Heller R, Fauler G, Kovacevic A, Nuszkowski A, Graier W, Sattler W, Malle E. Marsche G, et al. Among authors: fauler g. Arterioscler Thromb Vasc Biol. 2004 Dec;24(12):2302-6. doi: 10.1161/01.ATV.0000148703.43429.25. Epub 2004 Oct 28. Arterioscler Thromb Vasc Biol. 2004. PMID: 15514213
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M. Moustafa T, et al. Among authors: fauler g. Gastroenterology. 2012 Jan;142(1):140-151.e12. doi: 10.1053/j.gastro.2011.09.051. Epub 2011 Oct 14. Gastroenterology. 2012. PMID: 22001865
Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin.
Üllen A, Nusshold C, Glasnov T, Saf R, Cantillo D, Eibinger G, Reicher H, Fauler G, Bernhart E, Hallstrom S, Kogelnik N, Zangger K, Oliver Kappe C, Malle E, Sattler W. Üllen A, et al. Among authors: fauler g. Biochem Pharmacol. 2015 Feb 15;93(4):470-81. doi: 10.1016/j.bcp.2014.12.017. Epub 2015 Jan 6. Biochem Pharmacol. 2015. PMID: 25576489 Free PMC article.
Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Nusshold C, Üllen A, Kogelnik N, Bernhart E, Reicher H, Plastira I, Glasnov T, Zangger K, Rechberger G, Kollroser M, Fauler G, Wolinski H, Weksler BB, Romero IA, Kohlwein SD, Couraud PO, Malle E, Sattler W. Nusshold C, et al. Among authors: fauler g. Free Radic Biol Med. 2016 Jan;90:59-74. doi: 10.1016/j.freeradbiomed.2015.11.010. Epub 2015 Nov 11. Free Radic Biol Med. 2016. PMID: 26577177 Free PMC article.
104 results