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Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition.
Randino R, Moronese I, Cini E, Bizzarro V, Persico M, Grimaldi M, Scrima M, D'Ursi AM, Novellino E, Sobarzo-Sanchez E, Rastrelli L, Fattorusso C, Petrella A, Rodriquez M, Taddei M. Randino R, et al. Among authors: fattorusso c. Curr Top Med Chem. 2017;17(4):441-459. doi: 10.2174/1568026616666160824105645. Curr Top Med Chem. 2017. PMID: 27558677
Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.
Campiani G, Butini S, Trotta F, Fattorusso C, Catalanotti B, Aiello F, Gemma S, Nacci V, Novellino E, Stark JA, Cagnotto A, Fumagalli E, Carnovali F, Cervo L, Mennini T. Campiani G, et al. Among authors: fattorusso c. J Med Chem. 2003 Aug 28;46(18):3822-39. doi: 10.1021/jm0211220. J Med Chem. 2003. PMID: 12930145
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.
Campiani G, Fattorusso C, Butini S, Gaeta A, Agnusdei M, Gemma S, Persico M, Catalanotti B, Savini L, Nacci V, Novellino E, Holloway HW, Greig NH, Belinskaya T, Fedorko JM, Saxena A. Campiani G, et al. Among authors: fattorusso c. J Med Chem. 2005 Mar 24;48(6):1919-29. doi: 10.1021/jm049510k. J Med Chem. 2005. PMID: 15771436
Pyrrolo[1,5]benzoxa(thia)zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target.
Mc Gee MM, Gemma S, Butini S, Ramunno A, Zisterer DM, Fattorusso C, Catalanotti B, Kukreja G, Fiorini I, Pisano C, Cucco C, Novellino E, Nacci V, Williams DC, Campiani G. Mc Gee MM, et al. Among authors: fattorusso c. J Med Chem. 2005 Jun 30;48(13):4367-77. doi: 10.1021/jm049402y. J Med Chem. 2005. PMID: 15974589
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G. Fattorusso C, et al. J Med Chem. 2005 Nov 17;48(23):7153-65. doi: 10.1021/jm050257d. J Med Chem. 2005. PMID: 16279773
93 results