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Page 1
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.
Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B. Sala Frigerio C, et al. Among authors: fattorelli n. Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099. Cell Rep. 2019. PMID: 31018141 Free PMC article.
Stem-cell-derived human microglia transplanted in mouse brain to study human disease.
Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, Perry VH, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: fattorelli n. Nat Neurosci. 2019 Dec;22(12):2111-2116. doi: 10.1038/s41593-019-0525-x. Epub 2019 Oct 28. Nat Neurosci. 2019. PMID: 31659342
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
Vandermeulen L, Geric I, Fumagalli L, Kreir M, Lu A, Nonneman A, Premereur J, Wolfs L, Policarpo R, Fattorelli N, De Bondt A, Van Den Wyngaert I, Asselbergh B, Fiers M, De Strooper B, d'Ydewalle C, Mancuso R. Vandermeulen L, et al. Among authors: fattorelli n. Mol Neurodegener. 2024 Apr 24;19(1):37. doi: 10.1186/s13024-024-00725-9. Mol Neurodegener. 2024. PMID: 38654375 Free PMC article.
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology.
Mancuso R, Fattorelli N, Martinez-Muriana A, Davis E, Wolfs L, Van Den Daele J, Geric I, Premereur J, Polanco P, Bijnens B, Preman P, Serneels L, Poovathingal S, Balusu S, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: fattorelli n. Nat Neurosci. 2024 Mar 27. doi: 10.1038/s41593-024-01600-y. Online ahead of print. Nat Neurosci. 2024. PMID: 38539015
The γ-secretase substrate proteome and its role in cell signaling regulation.
Hou P, Zielonka M, Serneels L, Martinez-Muriana A, Fattorelli N, Wolfs L, Poovathingal S, T'Syen D, Balusu S, Theys T, Fiers M, Mancuso R, Howden AJM, De Strooper B. Hou P, et al. Among authors: fattorelli n. Mol Cell. 2023 Nov 16;83(22):4106-4122.e10. doi: 10.1016/j.molcel.2023.10.029. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977120 Free article.