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Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma.
Wu S, Fukumoto T, Lin J, Nacarelli T, Wang Y, Ong D, Liu H, Fatkhutdinov N, Zundell JA, Karakashev S, Zhou W, Schwartz LE, Tang HY, Drapkin R, Liu Q, Huntsman DG, Kossenkov AV, Speicher DW, Schug ZT, Van Dang C, Zhang R. Wu S, et al. Among authors: fatkhutdinov n. Nat Cancer. 2021 Feb;2(2):189-200. doi: 10.1038/s43018-020-00160-x. Epub 2021 Jan 11. Nat Cancer. 2021. PMID: 34085048 Free PMC article.
Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer.
Fukumoto T, Park PH, Wu S, Fatkhutdinov N, Karakashev S, Nacarelli T, Kossenkov AV, Speicher DW, Jean S, Zhang L, Wang TL, Shih IM, Conejo-Garcia JR, Bitler BG, Zhang R. Fukumoto T, et al. Among authors: fatkhutdinov n. Cell Rep. 2018 Mar 27;22(13):3393-3400. doi: 10.1016/j.celrep.2018.03.019. Cell Rep. 2018. PMID: 29590609 Free PMC article.
ARID1A promotes genomic stability through protecting telomere cohesion.
Zhao B, Lin J, Rong L, Wu S, Deng Z, Fatkhutdinov N, Zundell J, Fukumoto T, Liu Q, Kossenkov A, Jean S, Cadungog MG, Borowsky ME, Drapkin R, Lieberman PM, Abate-Shen CT, Zhang R. Zhao B, et al. Among authors: fatkhutdinov n. Nat Commun. 2019 Sep 6;10(1):4067. doi: 10.1038/s41467-019-12037-4. Nat Commun. 2019. PMID: 31492885 Free PMC article.
EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition.
Karakashev S, Fukumoto T, Zhao B, Lin J, Wu S, Fatkhutdinov N, Park PH, Semenova G, Jean S, Cadungog MG, Borowsky ME, Kossenkov AV, Liu Q, Zhang R. Karakashev S, et al. Among authors: fatkhutdinov n. Cancer Cell. 2020 Feb 10;37(2):157-167.e6. doi: 10.1016/j.ccell.2019.12.015. Epub 2020 Jan 30. Cancer Cell. 2020. PMID: 32004442 Free PMC article.
Potential therapeutic targets in ARID1A-mutated cancers.
Bitler BG, Fatkhutdinov N, Zhang R. Bitler BG, et al. Among authors: fatkhutdinov n. Expert Opin Ther Targets. 2015;19(11):1419-22. doi: 10.1517/14728222.2015.1062879. Epub 2015 Jun 30. Expert Opin Ther Targets. 2015. PMID: 26125128 Free PMC article. Review.
ARID1A spatially partitions interphase chromosomes.
Wu S, Fatkhutdinov N, Rosin L, Luppino JM, Iwasaki O, Tanizawa H, Tang HY, Kossenkov AV, Gardini A, Noma KI, Speicher DW, Joyce EF, Zhang R. Wu S, et al. Among authors: fatkhutdinov n. Sci Adv. 2019 May 22;5(5):eaaw5294. doi: 10.1126/sciadv.aaw5294. eCollection 2019 May. Sci Adv. 2019. PMID: 31131328 Free PMC article.
17 results