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Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania.
Grybchuk D, Akopyants NS, Kostygov AY, Konovalovas A, Lye LF, Dobson DE, Zangger H, Fasel N, Butenko A, Frolov AO, Votýpka J, d'Avila-Levy CM, Kulich P, Moravcová J, Plevka P, Rogozin IB, Serva S, Lukeš J, Beverley SM, Yurchenko V. Grybchuk D, et al. Among authors: fasel n. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E506-E515. doi: 10.1073/pnas.1717806115. Epub 2017 Dec 28. Proc Natl Acad Sci U S A. 2018. PMID: 29284754 Free PMC article.
Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response.
Brettmann EA, Shaik JS, Zangger H, Lye LF, Kuhlmann FM, Akopyants NS, Oschwald DM, Owens KL, Hickerson SM, Ronet C, Fasel N, Beverley SM. Brettmann EA, et al. Among authors: fasel n. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):11998-12005. doi: 10.1073/pnas.1615085113. Epub 2016 Oct 18. Proc Natl Acad Sci U S A. 2016. PMID: 27790981 Free PMC article.
Leishmania RNA virus: when the host pays the toll.
Hartley MA, Ronet C, Zangger H, Beverley SM, Fasel N. Hartley MA, et al. Among authors: fasel n. Front Cell Infect Microbiol. 2012 Jul 12;2:99. doi: 10.3389/fcimb.2012.00099. eCollection 2012. Front Cell Infect Microbiol. 2012. PMID: 22919688 Free PMC article. Review.
Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis.
Rossi M, Castiglioni P, Hartley MA, Eren RO, Prével F, Desponds C, Utzschneider DT, Zehn D, Cusi MG, Kuhlmann FM, Beverley SM, Ronet C, Fasel N. Rossi M, et al. Among authors: fasel n. Proc Natl Acad Sci U S A. 2017 May 9;114(19):4987-4992. doi: 10.1073/pnas.1621447114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28439019 Free PMC article.
Importance of polyphosphate in the Leishmania life cycle.
Kohl K, Zangger H, Rossi M, Isorce N, Lye LF, Owens KL, Beverley SM, Mayer A, Fasel N. Kohl K, et al. Among authors: fasel n. Microb Cell. 2018 Jun 22;5(8):371-384. doi: 10.15698/mic2018.08.642. Microb Cell. 2018. PMID: 30175107 Free PMC article.
Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis.
Ives A, Ronet C, Prevel F, Ruzzante G, Fuertes-Marraco S, Schutz F, Zangger H, Revaz-Breton M, Lye LF, Hickerson SM, Beverley SM, Acha-Orbea H, Launois P, Fasel N, Masina S. Ives A, et al. Among authors: fasel n. Science. 2011 Feb 11;331(6018):775-8. doi: 10.1126/science.1199326. Science. 2011. PMID: 21311023 Free PMC article.
Detection of Leishmania RNA virus in Leishmania parasites.
Zangger H, Ronet C, Desponds C, Kuhlmann FM, Robinson J, Hartley MA, Prevel F, Castiglioni P, Pratlong F, Bastien P, Müller N, Parmentier L, Saravia NG, Beverley SM, Fasel N. Zangger H, et al. Among authors: fasel n. PLoS Negl Trop Dis. 2013;7(1):e2006. doi: 10.1371/journal.pntd.0002006. Epub 2013 Jan 10. PLoS Negl Trop Dis. 2013. PMID: 23326619 Free PMC article.
137 results