Farrell NP - Search Results

1

Luminescent ruthenium complexes for theranostic applications.

Cardoso CR, Lima MV, Cheleski J, Peterson EJ, Venâncio T, Farrell NP, Carlos RM. Cardoso CR, et al. Among authors: farrell np. J Med Chem. 2014 Jun 12;57(11):4906-15. doi: 10.1021/jm5005946. Epub 2014 May 29. J Med Chem. 2014. PMID: 24831959

2

Novel transplatinum(II) complexes with [N2O2] donor sets. Cellular pharmacology and apoptosis induction in Pam 212-ras cells.

Quiroga AG, Pérez JM, Alonso C, Navarro-Ranninger C, Farrell N. Quiroga AG, et al. J Med Chem. 2006 Jan 12;49(1):224-31. doi: 10.1021/jm050804v. J Med Chem. 2006. PMID: 16392807

3

Effects of noncovalent platinum drug-protein interactions on drug efficacy: use of fluorescent conjugates as probes for drug metabolism.

Benedetti BT, Peterson EJ, Kabolizadeh P, Martínez A, Kipping R, Farrell NP. Benedetti BT, et al. Among authors: farrell np. Mol Pharm. 2011 Jun 6;8(3):940-8. doi: 10.1021/mp2000583. Epub 2011 May 16. Mol Pharm. 2011. PMID: 21548575 Free PMC article.

4

Heparan sulfate proteoglycan-mediated entry pathway for charged tri-platinum compounds: differential cellular accumulation mechanisms for platinum.

Silva H, Frézard F, Peterson EJ, Kabolizadeh P, Ryan JJ, Farrell NP. Silva H, et al. Among authors: farrell np. Mol Pharm. 2012 Jun 4;9(6):1795-802. doi: 10.1021/mp300098t. Epub 2012 May 2. Mol Pharm. 2012. PMID: 22494465 Free PMC article.

5

Exploring the DNA binding/cleavage, cellular accumulation and topoisomerase inhibition of 2-hydroxy-3-(aminomethyl)-1,4-naphthoquinone Mannich bases and their platinum(II) complexes.

Neves AP, Pereira MX, Peterson EJ, Kipping R, Vargas MD, Silva FP Jr, Carneiro JW, Farrell NP. Neves AP, et al. Among authors: farrell np. J Inorg Biochem. 2013 Feb;119:54-64. doi: 10.1016/j.jinorgbio.2012.10.007. Epub 2012 Oct 15. J Inorg Biochem. 2013. PMID: 23186648

6

Gold(I)-phosphine-N-heterocycles: biological activity and specific (ligand) interactions on the C-terminal HIVNCp7 zinc finger.

Abbehausen C, Peterson EJ, de Paiva RE, Corbi PP, Formiga AL, Qu Y, Farrell NP. Abbehausen C, et al. Among authors: farrell np. Inorg Chem. 2013 Oct 7;52(19):11280-7. doi: 10.1021/ic401535s. Epub 2013 Sep 24. Inorg Chem. 2013. PMID: 24063530

7

Ligand modulation of a dinuclear platinum compound leads to mechanistic differences in cell cycle progression and arrest.

Menon VR, Peterson EJ, Valerie K, Farrell NP, Povirk LF. Menon VR, et al. Among authors: farrell np. Biochem Pharmacol. 2013 Dec 15;86(12):1708-20. doi: 10.1016/j.bcp.2013.10.012. Epub 2013 Oct 24. Biochem Pharmacol. 2013. PMID: 24161784 Free PMC article.

8

A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding.

Mangrum JB, Engelmann BJ, Peterson EJ, Ryan JJ, Berners-Price SJ, Farrell NP. Mangrum JB, et al. Among authors: farrell np. Chem Commun (Camb). 2014 Apr 21;50(31):4056-8. doi: 10.1039/c3cc49695c. Chem Commun (Camb). 2014. PMID: 24463939 Free PMC article.

9

The bioinorganic chemistry of apoptosis: potential inhibitory zinc binding sites in caspase-3.

Daniel AG, Peterson EJ, Farrell NP. Daniel AG, et al. Among authors: farrell np. Angew Chem Int Ed Engl. 2014 Apr 14;53(16):4098-101. doi: 10.1002/anie.201311114. Epub 2014 Mar 18. Angew Chem Int Ed Engl. 2014. PMID: 24643997

10

Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.

Peterson EJ, Menon VR, Gatti L, Kipping R, Dewasinghe D, Perego P, Povirk LF, Farrell NP. Peterson EJ, et al. Among authors: farrell np. Mol Pharm. 2015 Jan 5;12(1):287-97. doi: 10.1021/mp5006867. Epub 2014 Dec 3. Mol Pharm. 2015. PMID: 25407898 Free PMC article.

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