Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1939 1
1944 2
1945 2
1949 2
1957 1
1958 1
1960 1
1961 1
1963 2
1964 1
1967 1
1969 1
1970 1
1971 2
1973 1
1974 1
1975 3
1976 2
1977 1
1978 2
1980 3
1983 1
1985 1
1988 1
1989 3
1990 1
1991 2
1992 3
1993 4
1995 2
1996 2
1997 4
1998 2
1999 2
2002 2
2003 3
2004 5
2005 2
2006 9
2007 8
2008 12
2009 7
2010 8
2011 11
2012 14
2013 15
2014 24
2015 16
2016 26
2017 14
2018 26
2019 25
2020 29
2021 36
2022 27
2023 21
2024 9

Text availability

Article attribute

Article type

Publication date

Search Results

367 results

Results by year

Filters applied: . Clear all
Page 1
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
Saul D, Kosinsky RL, Atkinson EJ, Doolittle ML, Zhang X, LeBrasseur NK, Pignolo RJ, Robbins PD, Niedernhofer LJ, Ikeno Y, Jurk D, Passos JF, Hickson LJ, Xue A, Monroe DG, Tchkonia T, Kirkland JL, Farr JN, Khosla S. Saul D, et al. Among authors: farr jn. Nat Commun. 2022 Aug 16;13(1):4827. doi: 10.1038/s41467-022-32552-1. Nat Commun. 2022. PMID: 35974106 Free PMC article.
Skeletal Aging.
Sfeir JG, Drake MT, Khosla S, Farr JN. Sfeir JG, et al. Among authors: farr jn. Mayo Clin Proc. 2022 Jun;97(6):1194-1208. doi: 10.1016/j.mayocp.2022.03.011. Mayo Clin Proc. 2022. PMID: 35662432 Free PMC article. Review.
Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: farr jn. Nature. 2023 Oct;622(7983):627-636. doi: 10.1038/s41586-023-06621-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821702 Free PMC article.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: farr jn. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Cellular senescence in bone.
Farr JN, Khosla S. Farr JN, et al. Bone. 2019 Apr;121:121-133. doi: 10.1016/j.bone.2019.01.015. Epub 2019 Jan 16. Bone. 2019. PMID: 30659978 Free PMC article. Review.
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, LeBrasseur NK, Wren JD, Farr JN, Khosla S, Stout MB, McGowan SJ, Fuhrmann-Stroissnigg H, Gurkar AU, Zhao J, Colangelo D, Dorronsoro A, Ling YY, Barghouthy AS, Navarro DC, Sano T, Robbins PD, Niedernhofer LJ, Kirkland JL. Zhu Y, et al. Among authors: farr jn. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25754370 Free PMC article.
The role of cellular senescence in ageing and endocrine disease.
Khosla S, Farr JN, Tchkonia T, Kirkland JL. Khosla S, et al. Among authors: farr jn. Nat Rev Endocrinol. 2020 May;16(5):263-275. doi: 10.1038/s41574-020-0335-y. Epub 2020 Mar 11. Nat Rev Endocrinol. 2020. PMID: 32161396 Free PMC article. Review.
Targeting cellular senescence prevents age-related bone loss in mice.
Farr JN, Xu M, Weivoda MM, Monroe DG, Fraser DG, Onken JL, Negley BA, Sfeir JG, Ogrodnik MB, Hachfeld CM, LeBrasseur NK, Drake MT, Pignolo RJ, Pirtskhalava T, Tchkonia T, Oursler MJ, Kirkland JL, Khosla S. Farr JN, et al. Nat Med. 2017 Sep;23(9):1072-1079. doi: 10.1038/nm.4385. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825716 Free PMC article.
Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism.
Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S. Weivoda MM, et al. Among authors: farr jn. Nat Commun. 2020 Jan 7;11(1):87. doi: 10.1038/s41467-019-14003-6. Nat Commun. 2020. PMID: 31911667 Free PMC article. Clinical Trial.
367 results