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In Vitro and In Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases.
Więckowska A, Szałaj N, Góral I, Bucki A, Latacz G, Kiec-Kononowicz K, Bautista-Aguilera ÒM, Romero A, Ramos E, Egea J, Farré Alíns V, González-Rodríguez Á, López-Muñoz F, Chioua M, Marco-Contelles J. Więckowska A, et al. Among authors: farre alins v. ACS Chem Neurosci. 2020 Nov 18;11(22):3793-3801. doi: 10.1021/acschemneuro.0c00489. Epub 2020 Nov 3. ACS Chem Neurosci. 2020. PMID: 33143412 Free PMC article.
Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.
Bautista-Aguilera ÓM, Hagenow S, Palomino-Antolin A, Farré-Alins V, Ismaili L, Joffrin PL, Jimeno ML, Soukup O, Janočková J, Kalinowsky L, Proschak E, Iriepa I, Moraleda I, Schwed JS, Romero Martínez A, López-Muñoz F, Chioua M, Egea J, Ramsay RR, Marco-Contelles J, Stark H. Bautista-Aguilera ÓM, et al. Among authors: farre alins v. Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12765-12769. doi: 10.1002/anie.201706072. Epub 2017 Sep 1. Angew Chem Int Ed Engl. 2017. PMID: 28861918
Neuroprotective effects of E-PodoFavalin-15999 (Atremorine®).
Romero A, Parada E, González-Lafuente L, Farré-Alins V, Ramos E, Cacabelos R, Egea J. Romero A, et al. Among authors: farre alins v. CNS Neurosci Ther. 2017 May;23(5):450-452. doi: 10.1111/cns.12693. Epub 2017 Mar 30. CNS Neurosci Ther. 2017. PMID: 28371323 Free PMC article. No abstract available.
Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux.
Farré-Alins V, Narros-Fernández P, Palomino-Antolín A, Decouty-Pérez C, Lopez-Rodriguez AB, Parada E, Muñoz-Montero A, Gómez-Rangel V, López-Muñoz F, Ramos E, González-Rodríguez Á, Gandía L, Romero A, Egea J. Farré-Alins V, et al. Antioxidants (Basel). 2020 Dec 18;9(12):1299. doi: 10.3390/antiox9121299. Antioxidants (Basel). 2020. PMID: 33353046 Free PMC article.
Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout.
Narros-Fernández P, Chioua M, Petcu SA, Diez-Iriepa D, Cerrada-Gálvez L, Decouty-Pérez C, Palomino-Antolín A, Ramos E, Farré-Alins V, López-Rodríguez AB, Romero A, Marco-Contelles J, Egea J. Narros-Fernández P, et al. Among authors: farre alins v. J Med Chem. 2022 Apr 28;65(8):6250-6260. doi: 10.1021/acs.jmedchem.2c00149. Epub 2022 Apr 11. J Med Chem. 2022. PMID: 35403430
Targeting Nrf2 in Protection Against Renal Disease.
Guerrero-Hue M, Farre-Alins V, Palomino-Antolin A, Parada E, Rubio-Navarro A, Egido J, Egea J, Moreno JA. Guerrero-Hue M, et al. Among authors: farre alins v. Curr Med Chem. 2017;24(33):3583-3605. doi: 10.2174/0929867324666170511120814. Curr Med Chem. 2017. PMID: 28494744 Review.
Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models.
Parada E, Casas AI, Palomino-Antolin A, Gómez-Rangel V, Rubio-Navarro A, Farré-Alins V, Narros-Fernandez P, Guerrero-Hue M, Moreno JA, Rosa JM, Roda JM, Hernández-García BJ, Egea J. Parada E, et al. Among authors: farre alins v. Br J Pharmacol. 2019 Aug;176(15):2764-2779. doi: 10.1111/bph.14703. Epub 2019 Jun 17. Br J Pharmacol. 2019. PMID: 31074003 Free PMC article.
16 results