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A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.
Kollmann S, Grausenburger R, Klampfl T, Prchal-Murphy M, Bastl K, Pisa H, Knab VM, Brandstoetter T, Doma E, Sperr WR, Lagger S, Farlik M, Moriggl R, Valent P, Halbritter F, Kollmann K, Heller G, Maurer B, Sexl V. Kollmann S, et al. Among authors: farlik m. Blood. 2021 Dec 9;138(23):2347-2359. doi: 10.1182/blood.2021010980. Blood. 2021. PMID: 34320169 Free PMC article.
Specification of tissue-resident macrophages during organogenesis.
Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F. Mass E, et al. Among authors: farlik m. Science. 2016 Sep 9;353(6304):aaf4238. doi: 10.1126/science.aaf4238. Epub 2016 Aug 4. Science. 2016. PMID: 27492475 Free PMC article.
DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation.
Farlik M, Halbritter F, Müller F, Choudry FA, Ebert P, Klughammer J, Farrow S, Santoro A, Ciaurro V, Mathur A, Uppal R, Stunnenberg HG, Ouwehand WH, Laurenti E, Lengauer T, Frontini M, Bock C. Farlik M, et al. Cell Stem Cell. 2016 Dec 1;19(6):808-822. doi: 10.1016/j.stem.2016.10.019. Epub 2016 Nov 17. Cell Stem Cell. 2016. PMID: 27867036 Free PMC article.
It is a differentiation game: STAT5 in a new role.
Maurer B, Farlik M, Sexl V. Maurer B, et al. Among authors: farlik m. Cell Death Differ. 2017 Jun;24(6):953-954. doi: 10.1038/cdd.2017.71. Epub 2017 May 12. Cell Death Differ. 2017. PMID: 28498368 Free PMC article. No abstract available.
STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT, Maurer B, Prchal-Murphy M, Grausenburger R, Grundschober E, Javaheri T, Nivarthi H, Boersma A, Kolbe T, Elabd M, Halbritter F, Pencik J, Kazemi Z, Grebien F, Hengstschläger M, Kenner L, Kubicek S, Farlik M, Bock C, Valent P, Müller M, Rülicke T, Sexl V, Moriggl R. Pham HTT, et al. Among authors: farlik m. J Clin Invest. 2018 Jan 2;128(1):387-401. doi: 10.1172/JCI94509. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29200404 Free PMC article.
An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.
Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, Sexl V, Bock C, Baccarini M. Baumgartner C, et al. Among authors: farlik m. Cell Stem Cell. 2018 Jun 1;22(6):879-892.e6. doi: 10.1016/j.stem.2018.05.003. Epub 2018 May 24. Cell Stem Cell. 2018. PMID: 29804890 Free PMC article.
CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.
Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, Mueller AC, Loizou JI, Hinds PW, Vogl C, Heller G, Kubicek S, Zuber J, Malumbres M, Farlik M, Villunger A, Kollmann K, Sexl V. Bellutti F, et al. Among authors: farlik m. Cancer Discov. 2018 Jul;8(7):884-897. doi: 10.1158/2159-8290.CD-17-0912. Epub 2018 Jun 13. Cancer Discov. 2018. PMID: 29899063 Free PMC article.
Epigenomics and Single-Cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis.
Halbritter F, Farlik M, Schwentner R, Jug G, Fortelny N, Schnöller T, Pisa H, Schuster LC, Reinprecht A, Czech T, Gojo J, Holter W, Minkov M, Bauer WM, Simonitsch-Klupp I, Bock C, Hutter C. Halbritter F, et al. Among authors: farlik m. Cancer Discov. 2019 Oct;9(10):1406-1421. doi: 10.1158/2159-8290.CD-19-0138. Epub 2019 Jul 25. Cancer Discov. 2019. PMID: 31345789 Free PMC article.
Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.
Santini L, Halbritter F, Titz-Teixeira F, Suzuki T, Asami M, Ma X, Ramesmayer J, Lackner A, Warr N, Pauler F, Hippenmeyer S, Laue E, Farlik M, Bock C, Beyer A, Perry ACF, Leeb M. Santini L, et al. Among authors: farlik m. Nat Commun. 2021 Jun 21;12(1):3804. doi: 10.1038/s41467-021-23510-4. Nat Commun. 2021. PMID: 34155196 Free PMC article.
60 results