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Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.
Nat Immunol. 2022 Jan;23(1):75-85. doi: 10.1038/s41590-021-01093-y. Epub 2021 Dec 22.
Nat Immunol. 2022.
PMID: 34937930
Free PMC article.
Clinical Trial.
Control of Immunity by the Microbiota.
Ansaldo E, Farley TK, Belkaid Y.
Ansaldo E, et al. Among authors: farley tk.
Annu Rev Immunol. 2021 Apr 26;39:449-479. doi: 10.1146/annurev-immunol-093019-112348.
Annu Rev Immunol. 2021.
PMID: 33902310
Review.
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Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring.
Lim AI, McFadden T, Link VM, Han SJ, Karlsson RM, Stacy A, Farley TK, Lima-Junior DS, Harrison OJ, Desai JV, Lionakis MS, Shih HY, Cameron HA, Belkaid Y.
Lim AI, et al. Among authors: farley tk.
Science. 2021 Aug 27;373(6558):eabf3002. doi: 10.1126/science.abf3002.
Science. 2021.
PMID: 34446580
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Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Lima-Junior DS, Krishnamurthy SR, Bouladoux N, Collins N, Han SJ, Chen EY, Constantinides MG, Link VM, Lim AI, Enamorado M, Cataisson C, Gil L, Rao I, Farley TK, Koroleva G, Attig J, Yuspa SH, Fischbach MA, Kassiotis G, Belkaid Y.
Lima-Junior DS, et al. Among authors: farley tk.
Cell. 2021 Jul 8;184(14):3794-3811.e19. doi: 10.1016/j.cell.2021.05.020. Epub 2021 Jun 23.
Cell. 2021.
PMID: 34166614
Free PMC article.
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Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis.
Kane SJ, Farley TK, Gordon EO, Estep J, Bender HR, Moreno JA, Bartz J, Telling GC, Pickering MC, Zabel MD.
Kane SJ, et al. Among authors: farley tk.
J Immunol. 2017 Dec 1;199(11):3821-3827. doi: 10.4049/jimmunol.1701100. Epub 2017 Oct 25.
J Immunol. 2017.
PMID: 29070671
Free PMC article.
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Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.
Schwartz DM, Farley TK, Richoz N, Yao C, Shih HY, Petermann F, Zhang Y, Sun HW, Hayes E, Mikami Y, Jiang K, Davis FP, Kanno Y, Milner JD, Siegel R, Laurence A, Meylan F, O'Shea JJ.
Schwartz DM, et al. Among authors: farley tk.
Immunity. 2019 Jan 15;50(1):106-120.e10. doi: 10.1016/j.immuni.2018.12.014.
Immunity. 2019.
PMID: 30650370
Free PMC article.
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Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling.
Geiger SS, Traba J, Richoz N, Farley TK, Brooks SR, Petermann F, Wang L, Gonzalez FJ, Sack MN, Siegel RM.
Geiger SS, et al. Among authors: farley tk.
Nat Commun. 2021 May 12;12(1):2745. doi: 10.1038/s41467-021-22961-z.
Nat Commun. 2021.
PMID: 33980856
Free PMC article.
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Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF.
Song YJ, Choi IA, Meylan F, Demoruelle MK, Farley T, Richard AC, Hawley E, Botson J, Hong YJ, Lee EY, Mian SR, Hamilton BC, Thiele GM, Mikuls TR, Gara N, Ward CD, Lamberth S, Deane KD, Heller T, Ward MM, Lee DM, Migone TS, Stohl W, O'Dell JR, Norris JM, Holers VM, Gregersen P, Song YW, Siegel RM.
Song YJ, et al.
Arthritis Res Ther. 2020 May 7;22(1):106. doi: 10.1186/s13075-020-02198-9.
Arthritis Res Ther. 2020.
PMID: 32381123
Free PMC article.
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