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Multiple-ascending doses of ACT-1014-6470, an oral complement factor 5a receptor 1 (C5a1 receptor) antagonist: Tolerability, pharmacokinetics and target engagement.
Anliker-Ort M, Dingemanse J, Farine H, Groenen P, Kornberger R, van den Anker J, Kaufmann P. Anliker-Ort M, et al. Among authors: farine h. Br J Clin Pharmacol. 2023 Jan;89(1):380-389. doi: 10.1111/bcp.15508. Epub 2022 Sep 7. Br J Clin Pharmacol. 2023. PMID: 36000981 Free article. Clinical Trial.
Impact of high-altitude therapy on type-2 immune responses in asthma patients.
Boonpiyathad T, Capova G, Duchna HW, Croxford AL, Farine H, Dreher A, Clozel M, Schreiber J, Kubena P, Lunjani N, Mirer D, Rückert B, Satitsuksanoa P, Tan G, Groenen PMA, Bersuch E, Akdis M, Strasser DS, Renner ED, Akdis CA. Boonpiyathad T, et al. Among authors: farine h. Allergy. 2020 Jan;75(1):84-94. doi: 10.1111/all.13967. Epub 2019 Nov 3. Allergy. 2020. PMID: 31267528
Plasma neurofilament light, glial fibrillary acidic protein and lysosphingolipid biomarkers for pharmacodynamics and disease monitoring of GM2 and GM1 gangliosidoses patients.
Welford RWD, Farine H, Steiner M, Garzotti M, Dobrenis K, Sievers C, Strasser DS, Amraoui Y, Groenen PMA, Giugliani R, Mengel E. Welford RWD, et al. Among authors: farine h. Mol Genet Metab Rep. 2022 Feb 1;30:100843. doi: 10.1016/j.ymgmr.2022.100843. eCollection 2022 Mar. Mol Genet Metab Rep. 2022. PMID: 35242574 Free PMC article.
Identification of cathepsin L as a potential sex-specific biomarker for renal damage.
Bauer Y, Hess P, Qiu C, Klenk A, Renault B, Wanner D, Studer R, Killer N, Stalder AK, Stritt M, Strasser DS, Farine H, Kauser K, Clozel M, Fischli W, Nayler O. Bauer Y, et al. Among authors: farine h. Hypertension. 2011 Apr;57(4):795-801. doi: 10.1161/HYPERTENSIONAHA.110.157206. Epub 2011 Feb 28. Hypertension. 2011. PMID: 21357272