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Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Li X, Knight J, Fargue S, Buchalski B, Guan Z, Inscho EW, Liebow A, Fitzgerald K, Querbes W, Todd Lowther W, Holmes RP. Li X, et al. Among authors: fargue s. Biochim Biophys Acta. 2016 Feb;1862(2):233-9. doi: 10.1016/j.bbadis.2015.12.001. Epub 2015 Dec 2. Biochim Biophys Acta. 2016. PMID: 26655602 Free PMC article.
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
Buchalski B, Wood KD, Challa A, Fargue S, Holmes RP, Lowther WT, Knight J. Buchalski B, et al. Among authors: fargue s. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165633. doi: 10.1016/j.bbadis.2019.165633. Epub 2019 Dec 7. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31821850 Free PMC article.
Future treatments for hyperoxaluria.
Burns Z, Knight J, Fargue S, Holmes R, Assimos D, Wood K. Burns Z, et al. Among authors: fargue s. Curr Opin Urol. 2020 Mar;30(2):171-176. doi: 10.1097/MOU.0000000000000709. Curr Opin Urol. 2020. PMID: 31895888 Free PMC article. Review.
End Points for Clinical Trials in Primary Hyperoxaluria.
Milliner DS, McGregor TL, Thompson A, Dehmel B, Knight J, Rosskamp R, Blank M, Yang S, Fargue S, Rumsby G, Groothoff J, Allain M, West M, Hollander K, Lowther WT, Lieske JC. Milliner DS, et al. Among authors: fargue s. Clin J Am Soc Nephrol. 2020 Jul 1;15(7):1056-1065. doi: 10.2215/CJN.13821119. Epub 2020 Mar 12. Clin J Am Soc Nephrol. 2020. PMID: 32165440 Free PMC article.
Effect of alanine supplementation on oxalate synthesis.
Wood KD, Freeman BL, Killian ME, Lai WS, Assimos D, Knight J, Fargue S. Wood KD, et al. Among authors: fargue s. Biochim Biophys Acta Mol Basis Dis. 2021 Jan 1;1867(1):165981. doi: 10.1016/j.bbadis.2020.165981. Epub 2020 Sep 28. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33002578 Free PMC article.
35 results