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Immunomodulatory and clinical effects of receptor-interacting protein kinase 1 (RIPK1) inhibitor eclitasertib (SAR443122) in patients with severe COVID-19: a phase 1b, randomized, double-blinded, placebo-controlled study.
Clot PF, Farenc C, Suratt BT, Krahnke T, Tardat A, Florian P, Pomponio R, Patel N, Wiekowski M, Lin Y, Terrier B, Staudinger H. Clot PF, et al. Among authors: farenc c. Respir Res. 2024 Feb 28;25(1):107. doi: 10.1186/s12931-024-02670-z. Respir Res. 2024. PMID: 38419035 Free PMC article. Clinical Trial.
Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Zareie P, Szeto C, Farenc C, Gunasinghe SD, Kolawole EM, Nguyen A, Blyth C, Sng XYX, Li J, Jones CM, Fulcher AJ, Jacobs JR, Wei Q, Wojciech L, Petersen J, Gascoigne NRJ, Evavold BD, Gaus K, Gras S, Rossjohn J, La Gruta NL. Zareie P, et al. Among authors: farenc c. Science. 2021 Jun 4;372(6546):eabe9124. doi: 10.1126/science.abe9124. Science. 2021. PMID: 34083463
MHC Restriction: Where Are We Now?
Zareie P, Farenc C, La Gruta NL. Zareie P, et al. Among authors: farenc c. Viral Immunol. 2020 Apr;33(3):179-187. doi: 10.1089/vim.2019.0195. Viral Immunol. 2020. PMID: 32286180 Free PMC article. No abstract available.
CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers.
Galperin M, Farenc C, Mukhopadhyay M, Jayasinghe D, Decroos A, Benati D, Tan LL, Ciacchi L, Reid HH, Rossjohn J, Chakrabarti LA, Gras S. Galperin M, et al. Among authors: farenc c. Sci Immunol. 2018 Jun 8;3(24):eaat0687. doi: 10.1126/sciimmunol.aat0687. Sci Immunol. 2018. PMID: 29884618
A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.
Van Braeckel-Budimir N, Gras S, Ladell K, Josephs TM, Pewe L, Urban SL, Miners KL, Farenc C, Price DA, Rossjohn J, Harty JT. Van Braeckel-Budimir N, et al. Among authors: farenc c. Immunity. 2017 Nov 21;47(5):835-847.e4. doi: 10.1016/j.immuni.2017.10.013. Epub 2017 Nov 14. Immunity. 2017. PMID: 29150238 Free PMC article.
A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors.
Sullivan LC, Walpole NG, Farenc C, Pietra G, Sum MJW, Clements CS, Lee EJ, Beddoe T, Falco M, Mingari MC, Moretta L, Gras S, Rossjohn J, Brooks AG. Sullivan LC, et al. Among authors: farenc c. J Biol Chem. 2017 Dec 22;292(51):21149-21158. doi: 10.1074/jbc.M117.807719. Epub 2017 Sep 25. J Biol Chem. 2017. PMID: 28972140 Free PMC article.
28 results