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Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis.
Bobowski-Gerard M, Boulet C, Zummo FP, Dubois-Chevalier J, Gheeraert C, Bou Saleh M, Strub JM, Farce A, Ploton M, Guille L, Vandel J, Bongiovanni A, Very N, Woitrain E, Deprince A, Lalloyer F, Bauge E, Ferri L, Ntandja-Wandji LC, Cotte AK, Grangette C, Vallez E, Cianférani S, Raverdy V, Caiazzo R, Gnemmi V, Leteurtre E, Pourcet B, Paumelle R, Ravnskjaer K, Lassailly G, Haas JT, Mathurin P, Pattou F, Dubuquoy L, Staels B, Lefebvre P, Eeckhoute J. Bobowski-Gerard M, et al. Among authors: farce a. Nat Commun. 2022 Sep 10;13(1):5324. doi: 10.1038/s41467-022-33063-9. Nat Commun. 2022. PMID: 36088459 Free PMC article.
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.
Rousseaux C, Lefebvre B, Dubuquoy L, Lefebvre P, Romano O, Auwerx J, Metzger D, Wahli W, Desvergne B, Naccari GC, Chavatte P, Farce A, Bulois P, Cortot A, Colombel JF, Desreumaux P. Rousseaux C, et al. Among authors: farce a. J Exp Med. 2005 Apr 18;201(8):1205-15. doi: 10.1084/jem.20041948. Epub 2005 Apr 11. J Exp Med. 2005. PMID: 15824083 Free PMC article.
Anti-diabetic activity of fused PPARγ-SIRT1 ligands with limited body-weight gain by mimicking calorie restriction and decreasing SGK1 expression.
Pirat C, Dacquet C, Leclerc V, Hennuyer N, Beucher-Gaudin M, Zanirato G, Géant A, Staels B, Ktorza A, Farce A, Caignard DH, Berthelot P, Lebegue N. Pirat C, et al. Among authors: farce a. Eur J Med Chem. 2017 Sep 8;137:310-326. doi: 10.1016/j.ejmech.2017.06.006. Epub 2017 Jun 12. Eur J Med Chem. 2017. PMID: 28609708
A computational view of COX-2 inhibition.
Chavatte P, Farce A. Chavatte P, et al. Among authors: farce a. Anticancer Agents Med Chem. 2006 May;6(3):239-49. doi: 10.2174/187152006776930909. Anticancer Agents Med Chem. 2006. PMID: 16712452 Review.
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARgamma agonists.
Blanc-Delmas E, Lebegue N, Wallez V, Leclerc V, Yous S, Carato P, Farce A, Bennejean C, Renard P, Caignard DH, Audinot-Bouchez V, Chomarat P, Boutin J, Hennuyer N, Louche K, Carmona MC, Staels B, Pénicaud L, Casteilla L, Lonchampt M, Dacquet C, Chavatte P, Berthelot P, Lesieur D. Blanc-Delmas E, et al. Among authors: farce a. Bioorg Med Chem. 2006 Nov 15;14(22):7377-91. doi: 10.1016/j.bmc.2006.07.029. Epub 2006 Aug 2. Bioorg Med Chem. 2006. PMID: 16887353
Homology modelling of the serotoninergic 5-HT2c receptor.
Farce A, Dilly S, Yous S, Berthelot P, Chavatte P. Farce A, et al. J Enzyme Inhib Med Chem. 2006 Jun;21(3):285-92. doi: 10.1080/14756360600700608. J Enzyme Inhib Med Chem. 2006. PMID: 16918076
69 results