Fang Z - Search Results

1

Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.

Tong X, Patel AS, Kim E, Li H, Chen Y, Li S, Liu S, Dilly J, Kapner KS, Zhang N, Xue Y, Hover L, Mukhopadhyay S, Sherman F, Myndzar K, Sahu P, Gao Y, Li F, Li F, Fang Z, Jin Y, Gao J, Shi M, Sinha S, Chen L, Chen Y, Kheoh T, Yang W, Yanai I, Moreira AL, Velcheti V, Neel BG, Hu L, Christensen JG, Olson P, Gao D, Zhang MQ, Aguirre AJ, Wong KK, Ji H. Tong X, et al. Among authors: fang z. Cancer Cell. 2024 Mar 11;42(3):413-428.e7. doi: 10.1016/j.ccell.2024.01.012. Epub 2024 Feb 22. Cancer Cell. 2024. PMID: 38402609 Free article.

2

LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response.

Li F, Han X, Li F, Wang R, Wang H, Gao Y, Wang X, Fang Z, Zhang W, Yao S, Tong X, Wang Y, Feng Y, Sun Y, Li Y, Wong KK, Zhai Q, Chen H, Ji H. Li F, et al. Among authors: fang z. Cancer Cell. 2015 May 11;27(5):698-711. doi: 10.1016/j.ccell.2015.04.001. Epub 2015 Apr 30. Cancer Cell. 2015. PMID: 25936644 Free PMC article.

3

The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.

Feng Y, Wang Y, Wang Z, Fang Z, Li F, Gao Y, Liu H, Xiao T, Li F, Zhou Y, Zhai Q, Liu X, Sun Y, Bardeesy N, Wong KK, Chen H, Xiong ZQ, Ji H. Feng Y, et al. Among authors: fang z. Cancer Res. 2012 Dec 15;72(24):6502-11. doi: 10.1158/0008-5472.CAN-12-1909. Epub 2012 Oct 16. Cancer Res. 2012. PMID: 23074285 Free PMC article.

4

NEDD9 promotes lung cancer metastasis through epithelial-mesenchymal transition.

Jin Y, Li F, Zheng C, Wang Y, Fang Z, Guo C, Wang X, Liu H, Deng L, Li C, Wang H, Chen H, Feng Y, Ji H. Jin Y, et al. Among authors: fang z. Int J Cancer. 2014 May 15;134(10):2294-304. doi: 10.1002/ijc.28568. Epub 2013 Nov 15. Int J Cancer. 2014. PMID: 24174333 Free article.

5

Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma.

Han X, Li F, Fang Z, Gao Y, Li F, Fang R, Yao S, Sun Y, Li L, Zhang W, Ma H, Xiao Q, Ge G, Fang J, Wang H, Zhang L, Wong KK, Chen H, Hou Y, Ji H. Han X, et al. Among authors: fang z, fang j, fang r. Nat Commun. 2014;5:3261. doi: 10.1038/ncomms4261. Nat Commun. 2014. PMID: 24531128 Free PMC article.

6

Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation.

Fang Z, Han X, Chen Y, Tong X, Xue Y, Yao S, Tang S, Pan Y, Sun Y, Wang X, Jin Y, Chen H, Hu L, Hui L, Li L, Chen L, Ji H. Fang Z, et al. Signal Transduct Target Ther. 2023 Jan 11;8(1):16. doi: 10.1038/s41392-022-01227-0. Signal Transduct Target Ther. 2023. PMID: 36627278 Free PMC article.

7

Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment.

Tang S, Xue Y, Qin Z, Fang Z, Sun Y, Yuan C, Pan Y, Zhao Y, Tong X, Zhang J, Huang H, Chen Y, Hu L, Huang D, Wang R, Zou W, Li Y, Thomas RK, Ventura A, Wong KK, Chen H, Chen L, Ji H. Tang S, et al. Among authors: fang z. Natl Sci Rev. 2023 Feb 14;10(4):nwad028. doi: 10.1093/nsr/nwad028. eCollection 2023 Apr. Natl Sci Rev. 2023. PMID: 37051524 Free PMC article.

8

EML4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation.

Qin Z, Yue M, Tang S, Wu F, Sun H, Li Y, Zhang Y, Izumi H, Huang H, Wang W, Xue Y, Tong X, Mori S, Taki T, Goto K, Jin Y, Li F, Li FM, Gao Y, Fang Z, Fang Y, Hu L, Yan X, Xu G, Chen H, Kobayashi SS, Ventura A, Wong KK, Zhu X, Chen L, Ren S, Chen LN, Ji H. Qin Z, et al. Among authors: fang y, fang z. J Exp Med. 2024 Mar 4;221(3):e20232028. doi: 10.1084/jem.20232028. Epub 2024 Jan 29. J Exp Med. 2024. PMID: 38284990

9

LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling.

Gao Y, Xiao Q, Ma H, Li L, Liu J, Feng Y, Fang Z, Wu J, Han X, Zhang J, Sun Y, Wu G, Padera R, Chen H, Wong KK, Ge G, Ji H. Gao Y, et al. Among authors: fang z. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18892-7. doi: 10.1073/pnas.1004952107. Epub 2010 Oct 18. Proc Natl Acad Sci U S A. 2010. PMID: 20956321 Free PMC article.

10

A network-based gene-weighting approach for pathway analysis.

Fang Z, Tian W, Ji H. Fang Z, et al. Cell Res. 2012 Mar;22(3):565-80. doi: 10.1038/cr.2011.149. Epub 2011 Sep 6. Cell Res. 2012. PMID: 21894192 Free PMC article.

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