Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.
Pfaffenbach M, Bolduc PN, Xin Z, Gao F, Evans R, Fang T, Chodaparambil JV, Henry KL, Li P, Mathieu S, Metrick C, Vera Rebollar JA, Gu RF, Mccarl CA, Silbereis J, Peterson EA.
Pfaffenbach M, et al. Among authors: fang t.
J Med Chem. 2024 May 2. doi: 10.1021/acs.jmedchem.4c00560. Online ahead of print.
J Med Chem. 2024.
PMID: 38695469