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Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression.
Wang R, Song S, Qin J, Yoshimura K, Peng F, Chu Y, Li Y, Fan Y, Jin J, Dang M, Dai E, Pei G, Han G, Hao D, Li Y, Chatterjee D, Harada K, Pizzi MP, Scott AW, Tatlonghari G, Yan X, Xu Z, Hu C, Mo S, Shanbhag N, Lu Y, Sewastjanow-Silva M, Fouad Abdelhakeem AA, Peng G, Hanash SM, Calin GA, Yee C, Mazur P, Marsden AN, Futreal A, Wang Z, Cheng X, Ajani JA, Wang L. Wang R, et al. Among authors: fan y. Cancer Cell. 2023 Aug 14;41(8):1407-1426.e9. doi: 10.1016/j.ccell.2023.06.005. Epub 2023 Jul 6. Cancer Cell. 2023. PMID: 37419119
Patient-derived cell lines and orthotopic mouse model of peritoneal carcinomatosis recapitulate molecular and phenotypic features of human gastric adenocarcinoma.
Song S, Xu Y, Huo L, Zhao S, Wang R, Li Y, Scott AW, Pizzi MP, Wang Y, Fan Y, Harada K, Jin J, Ma L, Yao X, Shanbhag ND, Gan Q, Roy-Chowdhuri S, Badgwell BD, Wang Z, Wang L, Ajani JA. Song S, et al. Among authors: fan y. J Exp Clin Cancer Res. 2021 Jun 23;40(1):207. doi: 10.1186/s13046-021-02003-8. J Exp Clin Cancer Res. 2021. PMID: 34162421 Free PMC article.
GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma.
Li Y, Fan Y, Xu J, Huo L, Scott AW, Jin J, Yang B, Shao S, Ma L, Wang Y, Yao X, Pool Pizzi M, Sewastjanow Da Silva M, Zhang G, Zhuo L, Cho EJ, Dalby KN, Shanbhag ND, Wang Z, Li W, Song S, Ajani JA. Li Y, et al. Among authors: fan y. J Exp Clin Cancer Res. 2022 Aug 23;41(1):257. doi: 10.1186/s13046-022-02463-6. J Exp Clin Cancer Res. 2022. PMID: 35996148 Free PMC article.
Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment.
Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, Calin GA, Mazur PK, Hanash SM, Ishizawa J, Hirata Y, Nagano O, Wang Z, Wang L, Xian W, McKeon F, Ajani JA, Song S. Fan Y, et al. Gut. 2023 Apr;72(4):624-637. doi: 10.1136/gutjnl-2021-326581. Epub 2022 Aug 24. Gut. 2023. PMID: 36002248
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