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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function.
Xu W, Billon C, Li H, Wilderman A, Qi L, Graves A, Rideb JRDC, Zhao Y, Hayes M, Yu K, Losby M, Hampton CS, Adeyemi CM, Hong SJ, Nasiotis E, Fu C, Oh TG, Fan W, Downes M, Welch RD, Evans RM, Milosavljevic A, Walker JK, Jensen BC, Pei L, Burris T, Zhang L. Xu W, et al. Among authors: fan w. Circulation. 2024 Jan 16;149(3):227-250. doi: 10.1161/CIRCULATIONAHA.123.066542. Epub 2023 Nov 14. Circulation. 2024. PMID: 37961903
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.
Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, Beutler B. Krebs P, et al. Among authors: fan w. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19678-82. doi: 10.1073/pnas.1117835108. Epub 2011 Nov 21. Proc Natl Acad Sci U S A. 2011. PMID: 22106289 Free PMC article.
Nuclear receptors and AMPK: resetting metabolism.
Fan W, Downes M, Atkins A, Yu R, Evans RM. Fan W, et al. Cold Spring Harb Symp Quant Biol. 2011;76:17-22. doi: 10.1101/sqb.2012.76.010470. Epub 2012 Mar 12. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22411605 Free PMC article. Review.
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Suh JM, et al. Among authors: fan w. Nature. 2014 Sep 18;513(7518):436-9. doi: 10.1038/nature13540. Epub 2014 Jul 16. Nature. 2014. PMID: 25043058 Free PMC article.
Turning up the heat on membrane fluidity.
Fan W, Evans RM. Fan W, et al. Cell. 2015 May 21;161(5):962-963. doi: 10.1016/j.cell.2015.04.046. Cell. 2015. PMID: 26000475 Free article.
High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice.
Wall CE, Whyte J, Suh JM, Fan W, Collins B, Liddle C, Yu RT, Atkins AR, Naviaux JC, Li K, Bright AT, Alaynick WA, Downes M, Naviaux RK, Evans RM. Wall CE, et al. Among authors: fan w. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8714-9. doi: 10.1073/pnas.1509930112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124126 Free PMC article.
6,534 results