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ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation.
Zhang D, De Veirman K, Fan R, Jian Q, Zhang Y, Lei L, Evans H, Wang Y, Lei L, Wang B, Williamson RA, Chantry A, He P, Li A, De Raeve H, Vanderkerken K, He A, Hu J. Zhang D, et al. Among authors: fan r. Stem Cell Res Ther. 2020 Nov 30;11(1):516. doi: 10.1186/s13287-020-02037-3. Stem Cell Res Ther. 2020. PMID: 33256835 Free PMC article.
Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.
Satilmis H, Verheye E, Vlummens P, Oudaert I, Vandewalle N, Fan R, Knight JM, De Beule N, Ates G, Massie A, Moreaux J, Maes A, De Bruyne E, Vanderkerken K, Menu E, Sloan EK, De Veirman K. Satilmis H, et al. Among authors: fan r. J Pathol. 2023 Jan;259(1):69-80. doi: 10.1002/path.6020. Epub 2022 Nov 22. J Pathol. 2023. PMID: 36245401 Free PMC article.
Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma.
Fan R, Satilmis H, Vandewalle N, Verheye E, Vlummens P, Maes A, Muylaert C, De Bruyne E, Menu E, Evans H, Chantry A, De Beule N, Hose D, Törngren M, Eriksson H, Vanderkerken K, Maes K, Breckpot K, De Veirman K. Fan R, et al. J Immunother Cancer. 2023 Jan;11(1):e005319. doi: 10.1136/jitc-2022-005319. J Immunother Cancer. 2023. PMID: 36650020 Free PMC article.
Hypoxia promotes osteosarcoma cell proliferation and migration through enhancing platelet-derived growth factor-BB/platelet-derived growth factor receptor-β axis.
Zhang D, Cui G, Sun C, Lei L, Lei L, Williamson RA, Wang Y, Zhang J, Chen P, Wang A, Fan R, Han S, Wang Y, Hu J. Zhang D, et al. Among authors: fan r. Biochem Biophys Res Commun. 2019 Apr 30;512(2):360-366. doi: 10.1016/j.bbrc.2019.03.040. Epub 2019 Mar 17. Biochem Biophys Res Commun. 2019. PMID: 30894277
Signaling controversy and future therapeutical perspectives of targeting sphingolipid network in cancer immune editing and resistance to tumor necrosis factor-α immunotherapy.
Sukocheva OA, Neganova ME, Aleksandrova Y, Burcher JT, Chugunova E, Fan R, Tse E, Sethi G, Bishayee A, Liu J. Sukocheva OA, et al. Among authors: fan r. Cell Commun Signal. 2024 May 2;22(1):251. doi: 10.1186/s12964-024-01626-6. Cell Commun Signal. 2024. PMID: 38698424 Free PMC article. Review.
3,200 results