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Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human.
Haghighi K, Kolokathis F, Pater L, Lynch RA, Asahi M, Gramolini AO, Fan GC, Tsiapras D, Hahn HS, Adamopoulos S, Liggett SB, Dorn GW 2nd, MacLennan DH, Kremastinos DT, Kranias EG. Haghighi K, et al. Among authors: fan gc. J Clin Invest. 2003 Mar;111(6):869-76. doi: 10.1172/JCI17892. J Clin Invest. 2003. PMID: 12639993 Free PMC article.
Hsp20 and its cardioprotection.
Fan GC, Chu G, Kranias EG. Fan GC, et al. Trends Cardiovasc Med. 2005 May;15(4):138-41. doi: 10.1016/j.tcm.2005.05.004. Trends Cardiovasc Med. 2005. PMID: 16099377 Review.
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.
Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, Lynch RA, Fan GC, Tsiapras D, Parekh RR, Dorn GW 2nd, MacLennan DH, Kremastinos DT, Kranias EG. Haghighi K, et al. Among authors: fan gc. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1388-93. doi: 10.1073/pnas.0510519103. Epub 2006 Jan 23. Proc Natl Acad Sci U S A. 2006. PMID: 16432188 Free PMC article.
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity.
Yuan Q, Fan GC, Dong M, Altschafl B, Diwan A, Ren X, Hahn HH, Zhao W, Waggoner JR, Jones LR, Jones WK, Bers DM, Dorn GW 2nd, Wang HS, Valdivia HH, Chu G, Kranias EG. Yuan Q, et al. Among authors: fan gc. Circulation. 2007 Jan 23;115(3):300-9. doi: 10.1161/CIRCULATIONAHA.106.654699. Epub 2007 Jan 15. Circulation. 2007. PMID: 17224479
207 results