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Virus-induced senescence is a driver and therapeutic target in COVID-19.
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter-Pechanska P, Wyler E, Belenki D, Kaltenbrunner S, Pammer M, Kausche L, Firsching TC, Dietert K, Schotsaert M, Martínez-Romero C, Singh G, Kunz S, Niemeyer D, Ghanem R, Salzer HJF, Paar C, Mülleder M, Uccellini M, Michaelis EG, Khan A, Lau A, Schönlein M, Habringer A, Tomasits J, Adler JM, Kimeswenger S, Gruber AD, Hoetzenecker W, Steinkellner H, Purfürst B, Motz R, Di Pierro F, Lamprecht B, Osterrieder N, Landthaler M, Drosten C, García-Sastre A, Langer R, Ralser M, Eils R, Reimann M, Fan DNY, Schmitt CA. Lee S, et al. Among authors: fan dny. Nature. 2021 Nov;599(7884):283-289. doi: 10.1038/s41586-021-03995-1. Epub 2021 Sep 13. Nature. 2021. PMID: 34517409
Senescence-associated reprogramming promotes cancer stemness.
Milanovic M, Fan DNY, Belenki D, Däbritz JHM, Zhao Z, Yu Y, Dörr JR, Dimitrova L, Lenze D, Monteiro Barbosa IA, Mendoza-Parra MA, Kanashova T, Metzner M, Pardon K, Reimann M, Trumpp A, Dörken B, Zuber J, Gronemeyer H, Hummel M, Dittmar G, Lee S, Schmitt CA. Milanovic M, et al. Among authors: fan dny. Nature. 2018 Jan 4;553(7686):96-100. doi: 10.1038/nature25167. Epub 2017 Dec 20. Nature. 2018. PMID: 29258294
Genotoxic Stress-Induced Senescence.
Fan DNY, Schmitt CA. Fan DNY, et al. Methods Mol Biol. 2019;1896:93-105. doi: 10.1007/978-1-4939-8931-7_10. Methods Mol Biol. 2019. PMID: 30474843
Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann M, Schrezenmeier J, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Lohneis P, Maßwig S, Denker S, Busse A, Knittel G, Flümann R, Childs D, Childs L, Gätjens-Sanchez AM, Bullinger L, Rosenwald A, Reinhardt HC, Schmitt CA. Reimann M, et al. Among authors: fan dny. Blood. 2021 May 20;137(20):2785-2799. doi: 10.1182/blood.2020005244. Blood. 2021. PMID: 33232972 Free article.
A cFLIP-flop switch for senolysis.
Fan DNY, Schmitt CA. Fan DNY, et al. Nat Cancer. 2022 Nov;3(11):1279-1281. doi: 10.1038/s43018-022-00455-1. Nat Cancer. 2022. PMID: 36414710 No abstract available.
16 results