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Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection.
Schuhenn J, Meister TL, Todt D, Bracht T, Schork K, Billaud JN, Elsner C, Heinen N, Karakoese Z, Haid S, Kumar S, Brunotte L, Eisenacher M, Di Y, Lew J, Falzarano D, Chen J, Yuan Z, Pietschmann T, Wiegmann B, Uebner H, Taube C, Le-Trilling VTK, Trilling M, Krawczyk A, Ludwig S, Sitek B, Steinmann E, Dittmer U, Lavender KJ, Sutter K, Pfaender S. Schuhenn J, et al. Among authors: falzarano d. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2111600119. doi: 10.1073/pnas.2111600119. Proc Natl Acad Sci U S A. 2022. PMID: 35131898 Free PMC article.
Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques.
de Wit E, Rasmussen AL, Falzarano D, Bushmaker T, Feldmann F, Brining DL, Fischer ER, Martellaro C, Okumura A, Chang J, Scott D, Benecke AG, Katze MG, Feldmann H, Munster VJ. de Wit E, et al. Among authors: falzarano d. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16598-603. doi: 10.1073/pnas.1310744110. Epub 2013 Sep 23. Proc Natl Acad Sci U S A. 2013. PMID: 24062443 Free PMC article.
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection.
Li W, Chen C, Drelich A, Martinez DR, Gralinski LE, Sun Z, Schäfer A, Kulkarni SS, Liu X, Leist SR, Zhelev DV, Zhang L, Kim YJ, Peterson EC, Conard A, Mellors JW, Tseng CK, Falzarano D, Baric RS, Dimitrov DS. Li W, et al. Among authors: falzarano d. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139569 Free PMC article.
SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney.
Francis ME, Goncin U, Kroeker A, Swan C, Ralph R, Lu Y, Etzioni AL, Falzarano D, Gerdts V, Machtaler S, Kindrachuk J, Kelvin AA. Francis ME, et al. Among authors: falzarano d. PLoS Pathog. 2021 Jul 15;17(7):e1009705. doi: 10.1371/journal.ppat.1009705. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34265022 Free PMC article.
Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets.
Francis ME, Richardson B, Goncin U, McNeil M, Rioux M, Foley MK, Ge A, Pechous RD, Kindrachuk J, Cameron CM, Richardson C, Lew J, Machtaler S, Cameron MJ, Gerdts V, Falzarano D, Kelvin AA. Francis ME, et al. Among authors: falzarano d. Sci Rep. 2021 Jul 15;11(1):14536. doi: 10.1038/s41598-021-93855-9. Sci Rep. 2021. PMID: 34267262 Free PMC article.
Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants.
Banerjee A, Lew J, Kroeker A, Baid K, Aftanas P, Nirmalarajah K, Maguire F, Kozak R, McDonald R, Lang A, Gerdts V, Straus SE, Gilbert L, Li AX, Mozafarihashjin M, Walmsley S, Gingras AC, Wrana JL, Mazzulli T, Colwill K, McGeer AJ, Mubareka S, Falzarano D. Banerjee A, et al. Among authors: falzarano d. Med. 2022 Jun 10;3(6):422-432.e3. doi: 10.1016/j.medj.2022.04.002. Epub 2022 Apr 14. Med. 2022. PMID: 35437520 Free PMC article.
84 results