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An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis.
Shahsavani M, Pronk RJ, Falk R, Lam M, Moslem M, Linker SB, Salma J, Day K, Schuster J, Anderlid BM, Dahl N, Gage FH, Falk A. Shahsavani M, et al. Among authors: falk r, falk a. Mol Psychiatry. 2018 Jul;23(7):1674-1684. doi: 10.1038/mp.2017.175. Epub 2017 Sep 19. Mol Psychiatry. 2018. PMID: 28924182
Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality.
Lam M, Moslem M, Bryois J, Pronk RJ, Uhlin E, Ellström ID, Laan L, Olive J, Morse R, Rönnholm H, Louhivuori L, Korol SV, Dahl N, Uhlén P, Anderlid BM, Kele M, Sullivan PF, Falk A. Lam M, et al. Among authors: falk a. Exp Cell Res. 2019 Oct 1;383(1):111469. doi: 10.1016/j.yexcr.2019.06.014. Epub 2019 Jul 12. Exp Cell Res. 2019. PMID: 31302032 Free article.
Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies.
Tanaka N, Kanatani S, Kaczynska D, Fukumoto K, Louhivuori L, Mizutani T, Kopper O, Kronqvist P, Robertson S, Lindh C, Kis L, Pronk R, Niwa N, Matsumoto K, Oya M, Miyakawa A, Falk A, Hartman J, Sahlgren C, Clevers H, Uhlén P. Tanaka N, et al. Among authors: falk a. Nat Biomed Eng. 2020 Sep;4(9):875-888. doi: 10.1038/s41551-020-0576-z. Epub 2020 Jun 29. Nat Biomed Eng. 2020. PMID: 32601394
Transcriptome and Proteome Profiling of Neural Induced Pluripotent Stem Cells from Individuals with Down Syndrome Disclose Dynamic Dysregulations of Key Pathways and Cellular Functions.
Sobol M, Klar J, Laan L, Shahsavani M, Schuster J, Annerén G, Konzer A, Mi J, Bergquist J, Nordlund J, Hoeber J, Huss M, Falk A, Dahl N. Sobol M, et al. Among authors: falk a. Mol Neurobiol. 2019 Oct;56(10):7113-7127. doi: 10.1007/s12035-019-1585-3. Epub 2019 Apr 13. Mol Neurobiol. 2019. PMID: 30989628 Free PMC article.
Models of the blood-brain barrier using iPSC-derived cells.
Delsing L, Herland A, Falk A, Hicks R, Synnergren J, Zetterberg H. Delsing L, et al. Among authors: falk a. Mol Cell Neurosci. 2020 Sep;107:103533. doi: 10.1016/j.mcn.2020.103533. Epub 2020 Jul 24. Mol Cell Neurosci. 2020. PMID: 32717317 Free article. Review.
Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy.
Čančer M, Hutter S, Holmberg KO, Rosén G, Sundström A, Tailor J, Bergström T, Garancher A, Essand M, Wechsler-Reya RJ, Falk A, Weishaupt H, Swartling FJ. Čančer M, et al. Among authors: falk a. Cell Stem Cell. 2019 Dec 5;25(6):855-870.e11. doi: 10.1016/j.stem.2019.10.005. Epub 2019 Nov 27. Cell Stem Cell. 2019. PMID: 31786016 Free PMC article.
Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells.
Susanto E, Marin Navarro A, Zhou L, Sundström A, van Bree N, Stantic M, Moslem M, Tailor J, Rietdijk J, Zubillaga V, Hübner JM, Weishaupt H, Wolfsberger J, Alafuzoff I, Nordgren A, Magnaldo T, Siesjö P, Johnsen JI, Kool M, Tammimies K, Darabi A, Swartling FJ, Falk A, Wilhelm M. Susanto E, et al. Among authors: falk a. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20127-20138. doi: 10.1073/pnas.1920521117. Epub 2020 Aug 3. Proc Natl Acad Sci U S A. 2020. PMID: 32747535 Free PMC article.
530 results