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Deciphering the Ets-1/2-mediated transcriptional regulation of F8 gene identifies a minimal F8 promoter for hemophilia A gene therapy.
Famà R, Borroni E, Merlin S, Airoldi C, Pignani S, Cucci A, Corà D, Bruscaggin V, Scardellato S, Faletti S, Pelicci G, Pinotti M, Walker GE, Follenzi A. Famà R, et al. Among authors: faletti s. Haematologica. 2021 Jun 1;106(6):1624-1635. doi: 10.3324/haematol.2019.239202. Haematologica. 2021. PMID: 32467137 Free PMC article.
Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients.
Osti D, Del Bene M, Rappa G, Santos M, Matafora V, Richichi C, Faletti S, Beznoussenko GV, Mironov A, Bachi A, Fornasari L, Bongetta D, Gaetani P, DiMeco F, Lorico A, Pelicci G. Osti D, et al. Among authors: faletti s. Clin Cancer Res. 2019 Jan 1;25(1):266-276. doi: 10.1158/1078-0432.CCR-18-1941. Epub 2018 Oct 4. Clin Cancer Res. 2019. PMID: 30287549 Free article.
LSD1-directed therapy affects glioblastoma tumorigenicity by deregulating the protective ATF4-dependent integrated stress response.
Faletti S, Osti D, Ceccacci E, Richichi C, Costanza B, Nicosia L, Noberini R, Marotta G, Furia L, Faretta MR, Brambillasca S, Quarto M, Bertero L, Boldorini R, Pollo B, Gandini S, Cora D, Minucci S, Mercurio C, Varasi M, Bonaldi T, Pelicci G. Faletti S, et al. Sci Transl Med. 2021 Dec 8;13(623):eabf7036. doi: 10.1126/scitranslmed.abf7036. Epub 2021 Dec 8. Sci Transl Med. 2021. PMID: 34878824
ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.
Ferrarese R, Izzo A, Andrieux G, Lagies S, Bartmuss JP, Masilamani AP, Wasilenko A, Osti D, Faletti S, Schulzki R, Yuan S, Kling E, Ribecco V, Heiland DH, Tholen S, Prinz M, Pelicci G, Kammerer B, Boerries M, Carro MS. Ferrarese R, et al. Among authors: faletti s. Life Sci Alliance. 2022 Nov 22;6(1):e202201400. doi: 10.26508/lsa.202201400. Print 2023 Jan. Life Sci Alliance. 2022. PMID: 36414381 Free PMC article.
Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation.
Antona A, Leo G, Favero F, Varalda M, Venetucci J, Faletti S, Todaro M, Mazzucco E, Soligo E, Saglietti C, Stassi G, Manfredi M, Pelicci G, Corà D, Valente G, Capello D. Antona A, et al. Among authors: faletti s. Cell Death Discov. 2023 Jun 29;9(1):201. doi: 10.1038/s41420-023-01502-1. Cell Death Discov. 2023. PMID: 37385999 Free PMC article.