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The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer.
Strand C, Bak M, Borgquist S, Chebil G, Falck AK, Fjällskog ML, Grabau D, Hedenfalk I, Jirström K, Klintman M, Malmström P, Olsson H, Rydén L, Stål O, Bendahl PO, Fernö M. Strand C, et al. Among authors: falck ak. Springerplus. 2013 Dec;2(1):111. doi: 10.1186/2193-1801-2-111. Epub 2013 Mar 14. Springerplus. 2013. PMID: 23560250 Free PMC article.
Histological grade provides significant prognostic information in addition to breast cancer subtypes defined according to St Gallen 2013.
Ehinger A, Malmström P, Bendahl PO, Elston CW, Falck AK, Forsare C, Grabau D, Rydén L, Stål O, Fernö M; South and South-East Swedish Breast Cancer Groups. Ehinger A, et al. Among authors: falck ak. Acta Oncol. 2017 Jan;56(1):68-74. doi: 10.1080/0284186X.2016.1237778. Epub 2016 Oct 20. Acta Oncol. 2017. PMID: 27762648 Clinical Trial.
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