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The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection.
Lécuyer D, Nardacci R, Tannous D, Gutierrez-Mateyron E, Deva Nathan A, Subra F, Di Primio C, Quaranta P, Petit V, Richetta C, Mostefa-Kara A, Del Nonno F, Falasca L, Marlin R, Maisonnasse P, Delahousse J, Pascaud J, Deprez E, Naigeon M, Chaput N, Paci A, Saada V, Ghez D, Mariette X, Costa M, Pistello M, Allouch A, Delelis O, Piacentini M, Le Grand R, Perfettini JL. Lécuyer D, et al. Among authors: falasca l. Front Immunol. 2023 Oct 18;14:1270081. doi: 10.3389/fimmu.2023.1270081. eCollection 2023. Front Immunol. 2023. PMID: 37920468 Free PMC article.
Pleural Mesothelial Cells Modulate the Inflammatory/Profibrotic Response During SARS-CoV-2 Infection.
Matusali G, Trionfetti F, Bordoni V, Nardacci R, Falasca L, Colombo D, Terri M, Montaldo C, Castilletti C, Mariotti D, Del Nonno F, Capobianchi MR, Agrati C, Tripodi M, Strippoli R. Matusali G, et al. Among authors: falasca l. Front Mol Biosci. 2021 Nov 26;8:752616. doi: 10.3389/fmolb.2021.752616. eCollection 2021. Front Mol Biosci. 2021. PMID: 34901152 Free PMC article.
Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis.
Nardacci R, Colavita F, Castilletti C, Lapa D, Matusali G, Meschi S, Del Nonno F, Colombo D, Capobianchi MR, Zumla A, Ippolito G, Piacentini M, Falasca L. Nardacci R, et al. Among authors: falasca l. Cell Death Dis. 2021 Mar 12;12(3):263. doi: 10.1038/s41419-021-03527-9. Cell Death Dis. 2021. PMID: 33712574 Free PMC article.
Transglutaminase 2 Regulates Innate Immunity by Modulating the STING/TBK1/IRF3 Axis.
Occhigrossi L, Rossin F, D'Eletto M, Farrace MG, Ciccosanti F, Petrone L, Sacchi A, Nardacci R, Falasca L, Del Nonno F, Palucci I, Smirnov E, Barlev N, Agrati C, Goletti D, Delogu G, Fimia GM, Piacentini M. Occhigrossi L, et al. Among authors: falasca l. J Immunol. 2021 May 15;206(10):2420-2429. doi: 10.4049/jimmunol.2001122. Epub 2021 May 3. J Immunol. 2021. PMID: 33941660
May macroglossia in COVID-19 be related not only to angioedema?
Colombo D, Del Nonno F, Nardacci R, Falasca L. Colombo D, et al. Among authors: falasca l. J Infect Public Health. 2022 Jan;15(1):112-115. doi: 10.1016/j.jiph.2021.10.026. Epub 2021 Nov 1. J Infect Public Health. 2022. PMID: 34764043 Free PMC article.
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection.
Séror C, Melki MT, Subra F, Raza SQ, Bras M, Saïdi H, Nardacci R, Voisin L, Paoletti A, Law F, Martins I, Amendola A, Abdul-Sater AA, Ciccosanti F, Delelis O, Niedergang F, Thierry S, Said-Sadier N, Lamaze C, Métivier D, Estaquier J, Fimia GM, Falasca L, Casetti R, Modjtahedi N, Kanellopoulos J, Mouscadet JF, Ojcius DM, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL. Séror C, et al. Among authors: falasca l. J Exp Med. 2011 Aug 29;208(9):1823-34. doi: 10.1084/jem.20101805. Epub 2011 Aug 22. J Exp Med. 2011. PMID: 21859844 Free PMC article.
Hepatic Failure in COVID-19: Is Iron Overload the Dangerous Trigger?
Del Nonno F, Nardacci R, Colombo D, Visco-Comandini U, Cicalini S, Antinori A, Marchioni L, D'Offizi G, Piacentini M, Falasca L. Del Nonno F, et al. Among authors: falasca l. Cells. 2021 May 4;10(5):1103. doi: 10.3390/cells10051103. Cells. 2021. PMID: 34064487 Free PMC article.
103 results